长春地区婴幼儿腹泻人类杯状病毒感染的调查  

The epidemiological study of human calicivirus of infants infected with diarrhea in Changchun Children's Hospital

作　　者：刘宇奇[1] 孙利炜[1] 王承训[1] 陈奇[1] 刘愉[1] 方肇寅 

机构地区：[1]长春市儿童医院,吉林130061 [2]中国疾病预防与控制中心病毒所肠道组

出　　处：《中国优生与遗传杂志》2010年第8期25-25,8,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的了解长春地区婴幼儿腹泻人类杯状病毒(Human calicivirus,HuCV)感染的流行情况。方法用RT-PCR法检测腹泻患儿粪便标本中HuCV。结果长春地区婴幼儿腹泻HuCV检出率为18%。HuCV腹泻以2岁以下儿童为主(占96%)。流行高峰季节为11月至次年3月。选择19株HuCV进行分子鉴定,16株属GII-4群,2株属GII-3群,另一株属GI-2群,表明GII-4群为本地区优势株。5岁以下儿童中HuCV腹泻在年龄和季节分布上都与轮状病毒腹泻很相似。结论长春地区婴幼儿杯状病毒感染的流行病学调查为我国病毒感染性腹泻的预防和控制提供科学依据。Objective：To explore the epidemic feature of HuCV in ChangChun area.Methods：By using RT-PCR,we detected HuCV in feces of infants infected with diarrhea.Results：The positive rate of HuCV is 17% in ChangChun area and the children below 2 years were susceptible population（96%）.The summit of epidemic curve was November to the following March.We selected 17 strains of HuCV to do molecular evaluation.15 strains belonged to GII-4,1 strain belonged to GII-3 and another strain belonged to GII-2.GII-4 was dominant strain in ChangChun area.The children below 5 years who infected HuCV were similar with the children who infected RV in the epidemic age and season.Conclusion：The study will provide the evidence of prevention control virus infectious diarrhea.

关 键 词：婴幼儿 杯状病毒 腹泻 

分 类 号：R725.1[医药卫生—儿科]