我院137例左氧氟沙星注射液不良反应报告分析  

Analysis of 137 Adverse Drug Reaction Cases Induced by Levofloxacin Injection in Our Hospital

作　　者：史红军[1] 张珍珍[1] 

机构地区：[1]江苏职工医科大学附属高淳人民医院,高淳县211300

出　　处：《中国药房》2010年第32期3033-3035,共3页China Pharmacy

摘　　要：目的:了解左氧氟沙星(LVFX)注射液不良反应(ADR)发生特点,促进临床合理用药。方法:检索、统计我院2006～2009年上报的LVFX注射液ADR137例,并利用Excel电子表格分别对其年龄、性别、用药情况及ADR的临床表现等进行分析。结果:ADR在用药各年龄段人群均可发生,但60岁以上人群发生率最高(32.85%),以皮肤及其附件(62.04%)和胃肠道系统(16.06%)损害为主,大部分为轻、中度ADR。结论:临床应加强LVFX注射液合理应用和ADR监测,保障患者用药安全。OBJECTIVE： To analyze the characteristics of adverse drug reaction （ADR） induced by Levofloxacin （LVFX） injection and to promote rational use of drugs in the clinic. METHODS： 137 LVFX injection-induced ADR cases reported in our hospital during 2006～2009 were collected and analyzed statistically with Excel in respect of age, gender, medication and clinical manifestation, etc. RESULTS： ADR cases occurred nearly in all ages of people, and 32.85% were appeared in people over 60 years. Main clinical manifestations were lesion of skin and its appedants （62.04%） and gastrointestinal injury （16.06%）. Most of them were mild and medium ADR. CONCLUSION： Great importance should be attached to the rational use of LVFX injection and ADR monitoring to guarantee the safety of patients.

关 键 词：左氧氟沙星 不良反应 分析 

分 类 号：R917[医药卫生—药物分析学]