四种诊断方法检测血吸虫病不同程度流行区的成本—效果评价  

Comprehensive Evaluation of Cost-effectiveness for Different Diagnostic Strategies in Schistosomiasis Japonica Endemic Areas Among Different Infectious Degrees

作　　者：何永康[1,2] 周欢[1,2] 喻鑫玲[1,2] 罗新松 林金莲[1,2] 李岳生 李毅[1,2] 

机构地区：[1]湖南省寄生虫病防治研究所 [2]湖南医科大学公共卫生学院

出　　处：《实用预防医学》1999年第3期161-163,共3页Practical Preventive Medicine

基　　金：JRMC资助

摘　　要：目的评价四种诊断方法在血吸虫病不同程度流行区的检测效果与成本。方法应用集卵孵化法（Ａ）、Ｋａｔｏ－ｋａｔｚ法（Ｂ）、立刻ＥＬＩＳＡ（Ｃ）和快速一步法ＥＩＡ（Ｄ），对血吸虫病流行为重（Ｈ）、中（Ｍ）、轻（Ｌ）度的三个村进行检测和经费核算。结果根据层次分析法综合评价四种方法在流行区的效果／成本（Ｅ／Ｃ）比值：Ａ为０．２４０、０．２４１、０．２４４，Ｂ为０．２６４、０．２６７、０．２７１，Ｃ为０．２９２、０．２８８、０．２６６，Ｄ为０．２９９、０．３０１、０．２８３。结论表明Ｄ法在三种流行区检测的效果最好，经费最少，效果／成本比值最大。Objective To assess the effectiveness and the cost of four diagnostic strategies in Schistosomiasis japonica endemic areas of different infectious degrees. Methods The hatching method(A),Kato-Katz method(B),quick ELISA(C),and EIA(D) were used to detect and to collect information on epidemiology and economics for Schistosomiasis japonica at three villages where the prevalence is heavy(H),moderate (M),and light(L),respectively. A model to evaluate cost-effectiveness was established comprehensively. Results The above three villages had been assessed respectively by the following formula:E(x)= n I=1 Wifi.The ratios of effectiveness/cost(E/C) were as follows:0.240,0.241,244,respectively,for method A;0.264,0.267, 0.271,respectively,for method B;0.292,0.288,0.266,respectively,for method C;0.299,0.301,0.283, respectively,for method D. Conclusion Method D is the best at heavy,moderate,and light endemic areas with the best effect,least funds and biggest effectiveness and cost ratio.

关 键 词：综合评价 血吸虫病 诊断 

分 类 号：R532.210.4[医药卫生—内科学]