通便方的通便机理研究  

A Study on the Cathartic Mechanism of Tongbian Fang

作　　者：王汝俊[1] 杜群[1] 邵庭荫[1] 巫燕莉[1] 黄伟坚[2] 唐明 

机构地区：[1]广州中医药大学脾胃研究所,广州510405 [2]广州中医药大学中药系,92级广州510405

出　　处：《广州中医药大学学报》1999年第2期145-147,共3页Journal of Guangzhou University of Traditional Chinese Medicine

摘　　要：为探讨通便方（由具益气健脾、养阴、润肠通便作用的白术、玄参等药物组成）的通便机理，观察了该方对阿托品、肾上腺素、盐酸吗啡引起小鼠小肠推进运动抑制的影响及小鼠肠道水分和离体肠管运动的影响。研究结果表明，通便方能拮抗肾上腺素、阿托品、盐酸吗啡引起小鼠小肠推进的抑制；能显著增加小鼠肠腔水分；对家兔离体十二指肠自发运动有兴奋作用，能拮抗肾上腺素引起的离体十二指肠运动抑制和乙酰胆碱引起离体回肠的强直性收缩。The cathartic mechanism of Tongbian Fang was studied in this article.The exprimental resultsshowed that Tongbian Fang had the antagonistic effect on the inhibition of small intestine propulsion induced by adrenaline, atropine and morphine hydrochloride in mice, increased the water volume in intestinal cavities,excited the spontaneous movement of rabbit duodenum in vitro,antagonized the adrenaline-induced inhibition of duodenum movement in vitro and the acetylcholine-induced contraction of ileum in vitro.

关 键 词：通便方 药理学 便秘 小肠 润下药 中医药疗法 

分 类 号：R256.350.5[医药卫生—中医内科学]