门诊患者慢性前列腺炎/慢性骨盆疼痛综合征危险因素分析  

CHRARACTERISTICS AND RISK FACTORS OF PROSTATITIS/CHRONIC PELVIC PAIN SYNDROME IN UROLOGICAL OUTPATIENTS

作　　者：卢智泉[1] 文娟[1] 史玉婷[1] 张黎月[1] 齐建军[1] 贺振权[2] 张国毅[1] 李志强[1] 

机构地区：[1]辽宁医学院预防医学教研室.锦州121001 [2]辽宁医学院附属第一医院泌尿外科

出　　处：《现代预防医学》2010年第16期3001-3003,共3页Modern Preventive Medicine

基　　金：辽宁省教育厅基金项目(001721591);辽宁医学院奥鸿大学生科技活动基金项目(2008D13)

摘　　要：[目的]调查门诊慢性前列腺炎/慢性骨盆疼痛综合征(CP/CPPS)患者的生活方式、个体疾病既往史以及精神心理等因素与CP/CPPS的关系。[方法]采用以医院为基础的病例对照研究方法,病例为2005年8月～2007年7月到临床泌尿外科门诊就诊并被确诊为CP/CPPS的612名男性患者,年龄为20～57岁;对照为同期入院,年龄相同的非CP/CPPS的612名门诊患者所组成。采用《美国国立卫生研究院慢性前列腺炎症状评分指数》(NIH-CPSI)评价患者对生活质量(QOL)的影响。应用多元Logistic模型计算出CP/CPPS与研究因素的比值比(OR)及其相对应的95%可信区间(CI)。[结果]QOL9～12分的397名患者中,324名为20～39岁,占81.61%。调整了年龄因素后,经多因素Logistic回归分析的结果表明:尿道炎、频繁手淫、无节制性生活、泌尿系外伤、固定体位、焦虑心理、长时间憋尿与CP发病有关联。[结论]大多数CP/CPPS患者生活质量受影响较大;随着年龄增长,患病人数逐渐减少。影响慢性前列腺炎发生的危险因素分别为尿道炎、无节制性生活、频繁手淫、泌尿外伤、固定体位(尤其是坐位/骑跨位)、焦虑心理和长时间憋尿。[Objective] To investigate the association between chronic prostatitis /chronic pelvic pain syndrome（CP/CPPS） in urological outpatients and lifestyle habits,medical history,and psychological factors. [Methods] We conducted this hospital-based case control study between August,2005 and July,2007. A total of 612 male aged 20-57 years’ residents who had been treated on account of CP /CPPS which was examined to confirm a final diagnosis in outpatient. A total of 612 patients who had been admitted to the same hospitals for many different diseases not related prostatic conditions were used as controls. All subjects were interviewed using National Institute of Health-Chronic Prostatitis Symptom Index（NIH-CPSI） . The influence of CP /CPPS on quality of life（QOL） was assessed with the NIH-CPSI. Odds ratios（OR） and the corresponding 95% confidence interval（CI） in relation to the various measures were estimated using unconditional multiple logistic regression models. Age adjusted ORs and 95% CIs by category of the risks developing CP /CPPS were calculated. [Results] In total 397 male patients for their total scores of QOL 9-12,324（81.61%） patients were 20～39 years. After age-adjusted,the results of multifactorial logistic regression analyses indicated that risk factors of chronic prostatitis were respectively related with urethritis,frequency masturbation,uncontrolled sexual activity,urinary system injury,fixed body position,anxious and long-time holding urine. [Conclusion] Chronic prostatitis has a significant impact on patient＇s QOL. The number of CP patients decreased with the increase of age. The results of multifactorial logistic regression analyses indicated that risk factors of chronic prostatitis were respectively related with urethritis,incontinence sexual activity,frequency masturbation,urinary system injury,fixed body position（especially long-time sitting or riding position） ,anxious and long-time holding urine.

关 键 词：慢性前列腺炎/慢性骨盆疼痛综合征 病例对照研究 固定体位 生活质量 

分 类 号：R697.3[医药卫生—泌尿科学]