FSHβ基因的多态性分布及其对大白猪产活仔数的影响  

Polymorphism of the FSHβ Gene and its Association with the Number Born Alive Trait in Large White

作　　者：刘远[1] 李良良[1] 莫小雨 王振华 李文献 雷明刚[1] 

机构地区：[1]华中农业大学动物科技学院,武汉430070 [2]宜昌正大畜牧有限公司,宜昌443000 [3]湖北天种畜牧股份有限公司,武汉430344

出　　处：《中国畜牧兽医》2010年第8期142-145,共4页China Animal Husbandry & Veterinary Medicine

基　　金：国家863计划项目(2006AA10Z1D6)资助

摘　　要：为了研究猪繁殖性状候选主效基因FSHβ在大白猪不同胎次中的遗传效应,并应用于大白猪繁殖性状的遗传改良,采用PCR方法检测了该基因在2个大白猪育种群共802头母猪中的多态性分布,并分析了其对产活仔数的影响,其中湖北天种公司大白猪群体样本数为472头,分析统计胎次1774胎,等位基因A的频率为0.447、等位基因B的频率为0.553;宜昌正大公司大白猪群为330头,分析统计胎次1644胎,等位基因A、B的频率分别为0.312、0.688。分析该位点的多态性与产活仔数的关系,结果发现,头胎不同基因型对产活仔数的影响为AB>BB>AA,二胎为AA>AB>BB,经产胎次和所有胎次均为AB>AA>BB,但差异均不显著。综合分析结果表明,A等位基因对大白猪产活仔数的影响要优于B等位基因,AB基因型母猪的产活仔数要优于其他2种基因型,提高生产猪群该基因的杂合子个体数比例有望取得更大的经济效益。To study the genetic effect of forllicular-stimulating hormone beta subumit （FSHβ） on the number born alive （NBA） trait and its application in pig reproduction trait selection, the polymorphism of FSHβ was detected by the method of PCR and association analysis between different genotypes and NBA trait were carried out in 802 Large white sows with 3418 parities from two commercial breeding pig companies which were Hubei Tianzhong and Yichang Zhengda. The frequency of A allele was 0.447 in the Hubei Tianzhong sows population and 0.312 in the Yichang Zhengda sows population. It was demonstrated that the effect of different genotypes of FSHβ loci on the NBA was ABBBAA at the first parity, AAABBB at the second parity and ABAABB at the later parities and all parities, respectively, but no significance was found between different genotypes. The results showed that the effect of A allele was better than B allele on the NBA in large white. The sows of AA genotype have more NBA than the sows of other genotypes. Thus, increasing the number of sows with AB genotype on the FSHβ loci might bring us more litter pigs in commercial pig production.

关 键 词：大白猪 FSHΒ 产活仔数 

分 类 号：Q78[生物学—分子生物学]