某院颅脑手术抗菌药物使用调查分析  

Clinical Utilization of Antibiotics in Craniocerebral Operations in a Hospital:Survey and Analysis

作　　者：于中华[1] 赵志刚[2] 张秉尧[1] 刘胜男[3] 

机构地区：[1]河北省廊坊市人民医院,廊坊市065000 [2]首都医科大学附属天坛医院药剂科,北京市100050 [3]首都医科大学药学系,北京市100069

出　　处：《中国医院用药评价与分析》2010年第8期696-698,共3页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:调查某院颅脑手术抗菌药物使用情况,对使用现状进行客观分析,促进科学合理用药。方法:回顾性调查某院神经外科2009年1月-2010年3月颅脑手术出院病历270例,记录相关信息,进行统计分析。结果:270例病例中全部使用了抗菌药物,涉及抗菌药物8大类32个品种,使用频率较高的是β-内酰胺及酶抑制剂、第3代头孢菌素和万古霉素。结论:某院颅脑手术用药选择不尽合理,预防用药档次高、时限超规定,治疗用药时限过长;手术给药时机不当;频繁换药缺乏病原学检查,无指征联合用药等。OBJECTIVES：To investigate the utilization of antibiotics for patients undergoing cranialcerebral operations in a hospital and analyze the status quo of the use of antibiotics to promote a scientific and rational use of antibiotics.METHODS：By a retrospective study, a total of 270 medical histories of patients in neurosurgery undergoing cranialcerebral operations who were discharged from Jan.2009 to Mar.2010 were reviewed with the relevant information recorded for a statistical analysis.RESULTS：All of the 270 patients received antibiotics,which totaled 8 categories and 32 varieties.The most frequently used antibiotics were β-lactam,β lactamase-inhibitors, the third generation cephalosporins and vancomycin.CONCLUSION：The utilization of antibiotics in the neurosurgery patients in the hospital was somewhat irrational including improper drug choice,high level of drugs in preventive medication,beyond specification in the time limit,prolonged medication time,inappropriate timing of administration, frequent change of drugs in the absence of etiology test and non-indicated drug combination etc.

关 键 词：颅脑手术 抗菌药物 调查分析 

分 类 号：R978.1[医药卫生—药品]