武汉地区ToRCH流行规律初探  

Preliminary study on ToRCH epidemic laws in Wuhan Region

作　　者：龚镇奎[1,2] 骆林[1,2] 肖红雨[1,2] 黄鹤[1,2] 李静[1,2] 周学文 谌树青[1,2] 

机构地区：[1]湖北省医学科学院病毒所 [2]湖北省卫生防疫站门诊部

出　　处：《中华实验和临床病毒学杂志》1999年第2期139-141,共3页Chinese Journal of Experimental and Clinical Virology

摘　　要：目的探讨武汉地区ＴｏＲＣＨ流行规律。方法采用检测血清中ＴｏＲＣＨ特异性ＩｇＭ抗体的血清学方法，对武汉地区正常人群ＴｏＲＣＨ感染的情况进行了全年度（１９９７年３月～１９９８年２月）逐月监测。结果弓形体（Ｔｏｘｏ）、风疹病毒（ＲｕＶ）、巨细胞病毒（ＣＭＶ）和单纯性疱疹（ＨＳＶ）ＩｇＭ全年的平均阳性率分别为５８％、７５％、４２％和４９％。同时显示出武汉地区ＴｏＲＣＨ流行具有３大特点：（１）ＲｕＶ流行有明显的季节变化，春季（３、４、５）月份感染率最高（８５％、１９５％、１４０％）；Ｔｏｘｏ、ＣＭＡ和ＨＳＶ季节变化不明显；（２）成年人多为无明显临床症状的不显性感染；（３）ＴｏＲＣＨ４项合并感染的情况普遍存在，本年度的合并感染率为２６％。结论ＲｕＶ对孕妇的感染易引起胎儿先天畸形，根据其季节流行特点，在春季孕妇尽量少到公共场所活动，以免孕妇遭ＲｕＶ感染。Objective To investigate the ToRCH epidemic law in Wuhan region. Methods The ToRCH infection in the normal populations of Wuhan region was inspected through a whole year (from Mar. 1997 to Feb. 1998) by detecting the specific IgM antibodies to ToRCH in sera. Results The results showed that in the whole year, the average positive rates of IgM aitibodies to Toxo, RuV, CMV and HSV were 5.8%, 7.5%, 4.2% and 4.9% respectively. Three characteristics of the ToRCH epidemic in the region were concluded: (1) The epidemic of RuV obviously changed with seasons. Its infection rates were the highest (8.5%, 19.5%, 14.0%) during spring (March, April and May). However, the changes of Toxo, CMV and HSV were not obvious with seasons; (2) The adult infections were mainly recessive, which had no apparent clinical symptoms; (3) The cross infections of the four pathogens were common, the crossreaction rate of the surveyed year was 2.6%. Conclusions RuV infection of pregnant woman may result in congenital malformation of the emlbryo. Accoroling to the seasonal epidemic charactaristics of RuV, women in pregnancy had better not to go to the public places during the sping seasons (March, April, May) as far as possible.

关 键 词：TORCH 流行病学 ELSIA 

分 类 号：R382.5[医药卫生—医学寄生虫学]