一些新型含氮、硫杂官能团的杯[4]芳烃衍生物的合成  

Syntheses of Some Novel Calix[4]arene Derivatives with Azo- and Sulfur-functional Groups

作　　者：张筱逸[1] 杨发福[1,2] 王艳华[1] 黄智胜[1] 蔡秀琴[3] 

机构地区：[1]福建师范大学化学与材料学院,福州350007 [2]福建师范大学福建省高分子材料重点实验室,福州350007 [3]渭南师范学院化学系,渭南714000

出　　处：《有机化学》2010年第8期1226-1229,共4页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.20402002);福建省自然科学基金(No.2009J01019);渭南师范学院(No.06YKZ014)资助项目

摘　　要：以杯[4]芳烃-1,3-二溴乙氧基衍生物1为合成平台,在K2CO3/MeCN体系中分别与乙醇胺、L-亮氨醇、2-巯基苯并咪唑、巯基乙酸乙酯反应,以49%～76%的产率合成了4种新型含氮、硫杂官能团的杯[4]芳烃衍生物2,4,5和6.化合物2进一步与异硫氰酸苯酯反应,以84%的产率得到了新型树枝状杯[4]芳烃氮、硫杂衍生物3.新化合物的结构与构象经元素分析、质谱、核磁共振谱等表征证实.By reacting calix[4]arene 1,3-bis-bromoethoxy derivative 1 with ethanolamine,L-leucinol,2-mercaptobenzimidazole,ethyl thioglycolate in K2CO3/MeCN system,four novel calix4arene derivatives with azo-and sulfur-functional groups 2,4,5 and 6 were prepared in 49%～76% yields.By reacting compound 2 with phenyl isothiocyanate further,novel dendritic calix[4]arene derivative 3 with azo-and sulfur-functional groups was obtained in 84% yield.The structures and conformations of new compounds were characterized by elemental analyses,ESI-MS,1H NMR,etc.

关 键 词：杯[4]芳烃 氮杂 硫杂 合成 

分 类 号：O625[理学—有机化学]