择期介入与药物治疗急性非ST段抬高性心肌梗死的预后比较  

Comparison of outcome in patients with non-ST-segment elevation myocardial infarction treated with selective percutaneous coronary intervention and drug respectively

作　　者：何俊[1] 倪杰[1] 郑建良[1] 曹东来[1] 何文兵[1] 

机构地区：[1]江苏省常熟市第一人民医院心内科,215500

出　　处：《重庆医学》2010年第17期2334-2335,2337,共3页Chongqing medicine

摘　　要：目的比较择期经皮冠状动脉介入(PCI)治疗与药物治疗急性非ST段抬高性心肌梗死(NSTEMI)的临床效果。方法将60例确诊的NSTEMI患者随机分为两组,一组28例给予药物治疗并行择期PCI治疗(观察组),另一组32例给予药物治疗(对照组)进行对比观察。结果观察组中14例为单支病变,12例为双支病变,2例为3支病变。植入1个支架16例,植入2个支架10例,植入3个支架2例。60例患者随访1年发现,观察组患者心绞痛发生率、心力衰竭发生率较对照组明显减少;观察组左室射血分数(LVEF)有增加趋势,但差异无统计学意义。结论在药物治疗的基础上择期PCI治疗可以进一步降低NSTE-MI患者的心绞痛及心力衰竭的发生率。而介入治疗可一定程度的增加左室射血分数。Objective To investigate the effect of selective percutaneous coronary intervention（PCI） and drug-eluting stent treatment in the patients with non-ST-segment elevation myocardial infarction（NSTEMI）,compared with medical treatment.Methods 60 patients,including 54 male patients,with NSTEMI were randomized into two groups.One group was given medical treatment,the another group was given selective PCI and drug-eluting stent in addition to medical treatment.The average time for PCI was（10.7±4.5）d after AMI.Results The patients in the PCI group were all treated with Firebird stent successfully.After one year follow-up,angina pectoris and heart failure was significantly reduced in the PCI group compared with the only medical treatment group.Conclusion Selective PCI in the patients with NSTEMI can reduce the morbidity of angina pectoris and heart failure.

关 键 词：择期经皮冠状动脉介入治疗 急性心肌梗死 药物治疗 

分 类 号：R542.22[医药卫生—心血管疾病] R540.46[医药卫生—内科学]