老年人谷氨酰转肽酶异常与代谢综合征危险因素及颈动脉硬化的关系  

Relationship between gamma-glutamyltransferase and risk factors for metabolic syndrome and carotid atherosclerosis in eldly

作　　者：吴政[1] 杨明[1] 黄春[1] 

机构地区：[1]福建医科大学附属协和医院干部病房,350001

出　　处：《中国老年保健医学》2010年第4期41-42,45,共3页Chinese Journal of Geriatric Care

摘　　要：目的探讨老年人谷氨酰转肽酶升高与代谢综合征危险因素及颈动脉硬化的关系。方法根据谷氨酰转肽酶的水平分为两组,分别测定体重指数、血压、血脂、血糖,用彩色多普勒超声仪测定颈动脉内膜中层厚度。结果在谷氨酰转肽酶升高组,体重指数、收缩压、舒张压、空腹血糖、餐后血糖、甘油三酯、胆固醇、低密度胆固醇均高于正常组(P<0.05或P<0.01),肥胖、高血压、糖尿病、高脂血症的检出率均高于正常组(P<0.05或P<0.01)。在谷氨酰转肽酶升高组,颈动脉内膜中层厚度及动脉硬化斑块的检出率也明显高于正常组(P<0.01)。结论谷氨酰转肽酶的升高与动脉硬化密切相关,其原因是代谢因素的综合作用的结果。Objective To investigate the relationship between GGT and metabolic syndrome,carotid atherosclerosis in eldly.Methods 183 elderly patients were divided into two groups according to GGT.Blood lipid,serum glucose,blood pressure,blood mass index （BMI）,and intima-media thickness（IMT） were measured.IMT were measured by ultrasonography.Relationship between Gamma-glutamyltransferase with metabolic factor and carotid atherosclerosis were analyzed.Results Blood lipid,serum glucose,blood pressure,blood mass index （BMI） were significantly higher in the high GGT group than that in the controls （P0.05,P0.01）.In high GGT group,the detection rate of hypertension,obesity,diabetic and dyslipidemia is higher than that in normal group （P0.05,P0.01）.IMT in high GGT group is thicker than that in normal group （P0.01）.Conclusion There is some correlation between serum glutamyltransferase （GGT） and atherosclerosis,its reason is metabolic factor coaction.

关 键 词：谷氨酰转肽酶 代谢综合征 颈动脉硬化 心血管疾病 

分 类 号：R589[医药卫生—内分泌]