合欢皂苷J_(20)的结构鉴定  

STRUCTURAL ELUCIDATION OF JULIBROSIDE J 20

作　　者：邹坤[1] 赵玉英[1] 王棓 徐峰[1] 张如意[1] 郑俊华[1] 

机构地区：[1]北京医科大学药学院天然药物学系

出　　处：《药学学报》1999年第7期522-525,共4页Acta Pharmaceutica Sinica

基　　金：国家自然科学基金

摘　　要：目的：研究合欢皮的化学成分及活性。方法：用现代色谱法分离合欢皮皂苷，用化学和现代波谱法，主要是二维核磁共振技术鉴定结构。结果及结论：分离并鉴定了一个新三萜皂苷，结构为３Ｏ［βＤ吡喃木糖基（１→２）αＬ吡喃阿拉伯糖基（１→６）βＤ吡喃葡糖基］２１Ｏ｛（６Ｓ）２反式２羟甲基６甲基６ＯβＤ吡喃木糖基２，７辛二烯酰基｝金合欢酸２８ＯβＤ吡喃葡糖基（１→３）［αＬ呋喃阿拉伯糖基（１→４）］αＬ吡喃鼠李糖基（１→２）βＤ吡喃葡糖基酯，命名为合欢皂苷Ｊ２０（ＪｕｌｉｂｒｏｓｉｄｅＪ２０）。AIM: To research the constituents and activities of Albizzia julibrissin . METHODS: The saponins were separated by using HPLC and the structures were identified on the basis of chemical and spectral analysis. RESULTS AND CONCLUSION: A new saponin was isolated and its structure was elucidated as 3 O [β D xylopyranosyl (1→2) α L arabinopyranosyl (1→6) β D glucopyranosyl] 21 O [(6S) 2 trans 2 hydroxymethyl 6 methyl 6 O β D xylopyranosyl 2,7 octadienoyl] acacic acid 28 O β D glucopyranosyl (1→3) [α L arabinofuranosyl (1→4)] α L rhamnopyranosyl (1→2) β D glucopyranosyl ester.

关 键 词：合欢 三萜皂苷 合欢皂苷J20 中药 

分 类 号：R282.710.3[医药卫生—中药学] R284.1[医药卫生—中医学]