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机构地区:[1]天津市中心妇产科医院子宫内膜异位症治疗中心,300052
出 处:《国际妇产科学杂志》2010年第4期291-293,共3页Journal of International Obstetrics and Gynecology
摘 要:目的:探讨腹壁切口子宫内膜异位症(EMs)的临床诊断、治疗及预防。方法:回顾性分析65例腹壁切口EMs患者的临床资料。年龄23~37岁,平均(30.7±3.6)岁,均为第1胎剖宫产术后,于剖宫产术后8~36个月时出现腹部切口痛,切口瘢痕处或切口瘢痕周围腹壁肿块。入院时距剖宫产术9个月~6年,肿块约1cm×2cm~4cm×4.5cm,边界欠清晰,质韧偏实,压痛明显,不活动。23例CA125轻度升高。结果:EMs病灶部位:49例完全位于脂肪层中,13例深达腹直肌,3例达腹膜。所有患者均在硬膜外麻醉下行腹壁异位病灶切除术,对5例病灶直径>4cm的患者先给予促性腺激素释放激素激动剂(GnRHa)类药物治疗3次(每28~32d用药1次)后再手术。术后随访4~20个月,术后用药3个月,全部患者症状完全消失,无一例复发。结论:腹壁切口EMs诊断相对容易。手术是首选的治疗方法,彻底切除病灶是治疗该病的关键,术后继续用药可以避免复发。剖宫产术中采取预防措施是减少该病发生的关键。Objective :To explore the clinical characteristics, treatment as well as prevention of abdominal wall endometriosis (AWE). Methods: 65 cases of AWE treated at Tianjin Central Hospital of Obstetrics and Gynecology from year 2008 to 2009 were reviewed. The average age was (30.7±3.6)years, range from 23 to 37 years. All of whom un- dergone the first cesarean section presented with pain and mass of cesarean scar 8 to 36 months after surgery, were hospitalized 9 to 72 months after surgery. The size of mass was from 1 cm × 2 cm to 4 cm × 4.5 cm. The characteris- tics of mass include unclear edge, solid,hard,tenderness and inmovable. In 23 cases, CA125 were mildly elevated. Results :All the cases were secondry to cesarean section. Of 65 cases with AWE,49 were located in adipose layer, 13 cases were as deep as rectus abdominis. Peritoneal were invaded in 3 cases. All cases were received surgical treatment while in 5 cases which lesion diameter 〉 4 cm were given gonadotropin releasing hormone agonist (GnRHa) treatment for 3 times (per 28-32 day)prior to surgery. No recurrence was observed during 4-20 month follow-up and postoperative administration for 3 months. Conclusions:AWE could be diagnosed according to its medical history, typical clinical manifestations as well as gynecological check-up. Surgical treatment is the preferred choice. A complete excision with clear margin is very important. Medicine treatment after operation can prevent recurrence. Appropriately preventive measure is important during cesarean section.
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