1,3,5-三乙酰基六氢均三嗪的小分子法合成反应机理研究  

Synthetic Mechanism for 1,3,5-Triacetyl-1,3,5-triazacyclohexane Synthesized Using Small-Molecule Method

作　　者：娄忠良[1] 王鹏[1] 孟子晖[1] 刘越[1] 覃光明[2] 葛忠学[2] 王伯周[2] 

机构地区：[1]北京理工大学化工与环境学院,北京100081 [2]西安近代化学研究所,西安710061

出　　处：《有机化学》2010年第7期1059-1062,共4页Chinese Journal of Organic Chemistry

基　　金：爆炸科学与技术国家重点实验室(No.KFJJ09-04)资助项目

摘　　要：1,3,5-三乙酰基六氢均三嗪(1,3,5-triacetyl-1,3,5-triazacyclohexane,TRAT)是高性能单质炸药黑索金的关键硝化前体.本研究以小分子三聚甲醛和乙腈为原料,浓硫酸为催化剂,合成了TRAT,产率为89%.合成并表征了N,N'-亚甲基二乙酰胺和未见报道的三乙酰基二亚甲基三胺.根据已得到的几个中间体,推测了TRAT合成反应的可能机理.1,3,5-Triacetyl-1,3,5-triazacyclohexane （TRAT） is the key synthetic precursor for hexahydro-1,3,5-trinitro-s-triazine （RDX）. TRAT was synthesized from 1,3,5-trioxane with acetonitrile using concentrated sulfuric acid as a catalyst with a yield of 89% by an improved method. The stable intermediates, methylene-bis-alkanecarboxamide and triacetyl-bismethylene-triamine never reported were synthesized. According to intermediates synthesized, synthetic mechanism for TRAT from small molecules was proposed.

关 键 词：黑索金 1 3 5-三乙酰基六氢均三嗪 反应机理 

分 类 号：O626[理学—有机化学]