一氧化碳中毒迟发性脑病临床和MRI研究  

Clinic and imaging characteristics of delayed encephalopathy after carbon monoxide poisoning

作　　者：武涛[1] 杨小军[2] 党根喜[1] 胡亚卓[1] 

机构地区：[1]西安高新医院神经内科,西安710075 [2]西安高新医院影像中心,西安710075

出　　处：《中国实用神经疾病杂志》2010年第15期10-12,共3页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨一氧化碳中毒迟发性脑病(DEACMP)的临床表现和磁共振成像(MRI)特点。方法回顾性分析35例DEACMP患者的临床表现、颅脑MRI资料。结果 DEACMP临床表现以认知功能损害、大小便失禁、锥体外系及锥体系功能损害为主,常以认知功能障碍为首发症状;颅脑MRI异常者34例,主要表现为双侧基底节变性坏死,大脑白质脱髓鞘,脑室周围白质和半卵圆中心双侧对称的点状、斑片状或融合病灶,T1WI呈低信号,T2WI呈高信号。结论 DEACMP的诊断主要依靠一氧化碳接触史和临床表现,MRI对诊断和鉴别诊断及病情评估有重要价值。Objective To discuss the clinic and imaging characteristics of delayed encephalopathy after carbon monoxide poisoning(DEACMP).Methods The clinic and MRI data of 35 patients with DEACMP were respectively analyzed.Results Clinical manifestations of cognitive impairment,incontinence,extrapyramidal system and pyramidal system dysfunction mainly often considered known as the first symptoms of dysfunction,34 cases with MRI abnormalities.The MRI showed that brain lesions in DEACMP were bilateral symmetric punctate,spotty or confluent foci within periventricular white matter and centrum semioval,which showed high signal intensity in T2-weighted and low signal intensity in T1-weighted.Conclusion The diagnosis of DEACMP mainly depends on case history and clinical manifestations and MRI features.MRI has an important value in diagnosis,differential diagnosis and severity assessment of DEACMP.

关 键 词：一氧化碳中毒 迟发性脑病 磁共振成像 

分 类 号：R595.1[医药卫生—内科学]