多囊卵巢综合征子宫内膜病变相关因素分析  

Analysis on Relative Factors of Endometrial Lesions of Patients with Polycystic Ovary Syndrome

作　　者：张学艳[1] 杨艳萍[1] 姜云霞[1] 曹信杰 丁宗强 逯静茹 关志宝 

机构地区：[1]河北省秦皇岛市海港医院,066000

出　　处：《中国误诊学杂志》2010年第25期6055-6056,共2页Chinese Journal of Misdiagnostics

基　　金：2009年河北省科技研究与发展计划项目(编号:09276150)

摘　　要：目的探讨多囊卵巢综合征(PCOS)子宫内膜病变相关因素。方法用组织学方法检测109例P-COS患者子宫内膜病理状态,同时测量人体学指标,检测内分泌激素、胰岛素、血糖,60例正常妇女为对照组,比较各组间的差异。结果子宫内膜的组织病理学诊断结果:A组50例,以子宫内膜单纯型增生为主;B组59例,以增生期为主。LH/FSH值、TI、R者A组、B组分别与对照组比较,BMI A组与对照组比较,差异均有统计学意义(P<0.01)。结论 PCOS子宫内膜病理改变以单纯型增生为主,肥胖、胰岛素抵抗、高睾酮是子宫内膜异常增生及癌变的重要因素。Objective To explore the relative factors of endometrial lesions of patients with polycystic ovary syndrome（PCOS）.Methods The endometrial pathological state of 109 patients was detected by histological method,and the anthropometry measurements and endocrine hormones、insulin and blood glucose were determinated in the same time.60 normal women were control,and the difference between groups was compared.Results The histopathologic diagnosis of endometrium：A group（n=50） was simple endometrial hyperplasias mainly;B group（n=59） was proliferative stage mainly.The LH/FSH、T and IR had a statistical difference（P0.05） compared A group、B group and control.The BMI had a statistical difference（P0.05） compared A group and control.Conclusion The endometrium histopathologic changes of patients with PCOS are simple hyperplasias mainly.The obesity、insulin resistance and high testosterone are important factors of abnormal hyperplasia of endometrium and cancerization.

关 键 词：多囊卵巢综合征/病理学 子宫内膜/病理学 

分 类 号：R711.75[医药卫生—妇产科学]