低场磁共振系统上基于质子共振频率的测温研究  

Research on Temperature Measurement Based on Proton Resonance Frequency at Low Field MR

作　　者：李璟 莫纪江[2] 陈武凡[2] 冯衍秋[2] 辛学刚[2] 

机构地区：[1]宁波鑫高益磁材有限公司,浙江宁波315400 [2]南方医科大学生物医学工程学院,广州510515

出　　处：《医疗卫生装备》2010年第8期15-17,共3页Chinese Medical Equipment Journal

基　　金：国家自然科学基金项目(30800254;30730036);广东省自然科学基金项目(06301304)

摘　　要：目的:研究在永磁低场环境下高精度、高时间分辨率的磁共振温度监测。方法:利用基于质子共振频率化学位移的测温方法,在国产0.4T永磁磁共振设备上采用Flash序列采集琼脂凝胶降温过程的数据,并与玻璃温度计的测量结果进行对比。结果:对比温度计读数,磁共振测温实验结果达到头线圈±1.5℃,体线圈±2℃的精度;每次扫描时间为6s。结论:在永磁低场上,基于质子共振频率化学位移测温方法的精度能满足临床要求,时间分辨率能初步满足临床要求,尚需进一步提高。Objective To research the MR thermometry with high precision and high time resolution at low field MR.Methods The temperature of the cooling process of agar gel phantom was monitored using the method based on proton resonance frequency with 0.4 T home-built permanent MR equipment and Flash sequence,and then the results were compared with those of the thermometer.Results Compared with the thermometer readings,there was a temperature uncertainty as ±1.5 ℃ for head coil and ±2 ℃ for body coil.Scanning duration was 6 seconds.Conclusion The method of MR thermometry at low field based on chemical shifting of PRF with a high accuracy appears to be a viable technique for clinical application.But temporal resolution still needs to improve.

关 键 词：磁共振温度测量 质子共振频率 Flash序列 肿瘤热治疗 

分 类 号：R445.2[医药卫生—影像医学与核医学]