热习服干预对沙漠军训官兵胃肠激素和细胞免疫状况的影响  

Effects of Heat Acclimatization on Gastrointestinal Hormone and Cellular Immune Function of Soldiers in Desert Training

作　　者：惠华强[1] 姜文亭[1] 雷权[1] 黄文[2] 肖立宁 

机构地区：[1]兰州军区乌鲁木齐总医院医务部,新疆乌鲁木齐830000 [2]第二军医大学第一附属医院野战内科学研究所

出　　处：《华南国防医学杂志》2010年第4期281-282,288,共3页Military Medical Journal of South China

基　　金：全军"十一五"医药卫生科技重点基金项目(06Z026);全军"十一五"医药卫生科研攻关基金项目(06G057)

摘　　要：目的探讨热习服干预对沙漠军训官兵血浆胃肠激素和细胞免疫状况的影响。方法 140名在沙漠军训官兵随机均分为热习服干预组和对照组。对热习服组70名官兵进行热习服干预12d,均执行2个月的夏训任务;放射免疫法检测军训前后血浆胃动素(motilin,MTL)、血管活性肠肽(vasoactive intestinal peptide,VIP)和生长抑素(somatostain,SS)水平,流式细胞仪检测外周血T淋巴细胞亚群和自然杀伤细胞(natural killer cell,NK细胞)数量的变化。结果热习服干预组官兵军训前后血浆MTL、VIP和SS水平无显著性差异(P>0.05),对照组沙漠军训后血清MTL较军训前明显增高,VIP和SS水平显著降低(P<0.05);军训后热干预组官兵CD3+、CD4+、CD4+/CD8+及NK细胞明显高于对照组(P<0.05)。结论适当热习服干预能有效提高军训官兵胃肠功能稳定性和细胞免疫功能。Objective To study the effects of heat acclimatization on gastrointestinal hormone and cellular immune function of soldiers in desert training. Methods One hundred and forty soldiers in desert training were randomly and meanly divided into 2 groups： the heat acclimatization group and the control group. The heat acclimatization group trained in hot climatic chamber and dressed in military raincoat out of doors for 12 days. Then both the two groups of soldier trained in desert for 2 months. The plasma level of motilin （MTL）, vasoactive intestinal peptide （VIP） and somatostatin （SS） of the soldiers were evaluated by radioimmunoassay before and after desert training. The percentage of T, B and natural killer cell （NK） subpopulations were assessed by flow cytometry.Results There was not significant difference in MTL, VIP and SS levels before and after desert training （P0.05）. After desert training, MTL level of control group was significantly increased while VIP and SS was significantly decreased （P0.05）. Compared with control group, the percentage of CD3＋, CD4＋, CD4＋/CD8＋ of the heat acclimatization group elevated significantly （P0.05）. ConclusionSuitable heat acclimatization is beneficial to the function of gastrointestinal system and cellular immune of the soldiers in desert training.

关 键 词：热习服 沙漠 胃肠激素 细胞免疫 

分 类 号：R821[医药卫生—临床医学] R339.53