3,4,5-三甲氧基苯甲醛标准样品的研制  

Preparation of 3,4,5-Trimethoxy-benzaldehyde as Reference Substance

作　　者：汪咏梅[1,2] 陈笳鸿[1] 张亮亮[1,2] 吴冬梅[1,2] 徐曼[1] 吴在嵩[1] 

机构地区：[1]中国林业科学研究院林产化学工业研究所 生物质化学利用国家工程实验室 国家林业局林产化学工程重点开放性实验室 江苏省生物质能源与材料重点实验室,江苏南京210042 [2]中国林业科学研究院林业新技术研究所,北京100091

出　　处：《林产化学与工业》2010年第4期25-28,共4页Chemistry and Industry of Forest Products

基　　金：科技基础性工作专项(2007FY230200)

摘　　要：研究了3,4,5-三甲氧基苯甲醛标准样品的制备、均匀性和稳定性及其定值试验。用3,4,5-三甲氧基苯甲醛工业品与亚硫酸氢钠溶液加成反应,经H2SO4酸化,结晶;再用乙醇溶解,纯水稀释重结晶,得到高纯度的3,4,5-三甲氧基苯甲醛标准样品。标准样品含量测定采用气相色谱面积归一化法,并通过了均匀性检验和稳定性检验（9个月）。经定值检测,3,4,5-三甲氧基苯甲醛标准样品的质量分数为99.42%±0.07%。Preparation, homogeneity, stability and certification of reference substance of 3,4,5-trimethoxy-benzaldehyde were studied. Highly purified reference substance of 3,4,5-trimethoxy-benzaldehyde was prepared from an industrial grade 3,4,5-trimethoxy-benzaldehyde product by NaHSO3 addition reaction followed by acidifying with H2SO4 and re-crystallization in ethanol and water. The content of 3,4,5-trimethoxy-benzaldehyde in reference substance was measured by gas chromatographic area normalization. The reference substance of 3,4,5-trimethoxy-benzaldehyde passed the test of homogeneity, and it was stable during 9 months at least. Through valuation test, 3,4,5-trimethoxy-benzaldehyde content of the reference substance was 99.42%±0.07%.

关 键 词：3 4 5-三甲氧基苯甲醛 标准样品 定值 均匀性检验 

分 类 号：TQ351.0[化学工程]