两种高热稳定性端羟基单阳离子型咪唑离子液体毛细管气相色谱固定相的性能评价  

Evaluation of two hydroxyl-terminated monocationic ionic liquid stationary phases with high thermal stability for capillary gas chromatography

作　　者：卢凯[1] 刘伟[1,2] 齐美玲[1] 李言[1] 傅若农[1] 

机构地区：[1]北京理工大学理学院化学系,北京100081 [2]北京市疾病预防控制中心营养与食品卫生所,北京100013

出　　处：《色谱》2010年第8期731-736,共6页Chinese Journal of Chromatography

基　　金：国家自然科学基金项目(No.20675007)

摘　　要：采用静态法将合成的端羟基单阳离子咪唑离子液体1-(6-羟己基)-3-丁基咪唑二(三氟甲基)磺酰亚胺盐(HHBIM-NTf2)和1-(8-羟辛基)-3-丁基咪唑二(三氟甲基)磺酰亚胺盐(HOBIM-NTf2)作为固定相制备离子液体毛细管气相色谱柱。采用Grob试剂、混合醇样品和芳香族异构体混合物对固定相色谱选择性进行了考察,Grob试剂和混合醇组分产生的尖锐、对称的色谱峰形及异构体混合物组分达到基线分离的结果均表明端羟基离子液体固定相具有良好的色谱选择性。HHBIM-NTf2柱和HOBIM-NTf2柱经250℃老化8h后对异构体混合物的分离能力没有明显下降,而HHBIM-NTf2柱经300℃老化后仍有理想的异构体选择性,表明端羟基离子液体固定相具有理想的热稳定性。本结果为进一步改善单阳离子型咪唑离子液体固定相的色谱性能提供了有效途径。Novel hydroxyl-terminated ionic liquids of 1-（ 6-hydroxyhexyl） -3-butyl imidazolium bis（ trifluoromethyl） sulfonylimide （ HHBIM-NTf2） and 1-（ 8-hydroxyoctyl） -3-butyl imidazolium bis（ trifluoromethyl） sulfonylimide （ HOBIM-NTf2） were synthesized as stationary phases for capillary gas chromatography （ GC） . Besides,1-octyl-3-butyl imidazolium bis（ trifluoromethyl） sulfonylimide （ OBIM-NTf2） was used as the reference. Selectivities and thermal stabilities of HHBIM-NTf2,HOBIM-NTf2 and OBIM-NTf2 were evaluated by means of the separation of Grob test mixture and positional isomers after the columns were conditioned up to 160 ℃,250 ℃ and 300 ℃,respectively. As a result,baseline separations of Grob test mixture and alcohol mixture and better peak shapes were observed with HHBIM-NTf2 and HOBIMNTf2. Importantly,baseline separation of dimethoxybenzene isomers was also achieved with HHBIM-NTf2 and HOBIM-NTf2. Satisfactory selectivity of HHBIM-NTf2 still remained even after conditioned at 300 ℃ for 8 h. The results for thermal stability showed that as GC stationary phases,HHBIM-NTf2 and HOBIMNTf2 were stable at least up to 300 ℃ and 250 ℃,respectively. The hydroxyl-terminated monocationic ionic liquids possess excellent selectivity and thermal stability and are alternative candidates for GC stationary phases.

关 键 词：毛细管气相色谱 端羟基离子液体 固定相 

分 类 号：O658[理学—分析化学]