我院抗骨质疏松药物用药趋势分析及合理应用评价  

Analysis and evaluation of anti-osteoporosis drugs use in our hospital

作　　者：吕慧怡[1] 范青[1] 田燕[2] 张宁[1] 

机构地区：[1]大连医科大学附属第二医院药剂科,大连116027 [2]大连医科大学药学院,大连116044

出　　处：《实用药物与临床》2010年第4期275-277,共3页Practical Pharmacy and Clinical Remedies

摘　　要：目的分析我院抗骨质疏松药的利用情况,为临床合理使用提供参考。方法根据抗骨质疏松药的结构及作用机制不同进行分类,采用WHO推荐的限定日剂量(Defined Daily Dose,DDD)频度分析法,对我院2006年8月-2009年7月抗骨质疏松药的销售金额、用药频度及日均费用等进行回顾性分析。结果我院抗骨质疏松药中,碳酸钙片用药频度最高,双膦酸盐类增长迅速;日均费用唑来磷酸注射液最高。结论抗骨质疏松药物应用情况调查对促进抗骨质疏松药的合理应用及临床用药监护具有重要意义。Objective To analyze the trend of anti-osteoporosis drugs use in our hospital,promote the clinical rational use of them. Methods According to the different structures and mechanisms of classification in anti-osteoporosis drugs,the anti-osteoporosis drug sales amounts,frequency and daily drug costs in our hospital from August 2006 to July 2009 were analyzed retrospectively using WHO defined daily dose recommended（ Definded Daily Dose,DDD） frequency analysis. Results The DDDs frequency of calcium carbonate tablets was the highest in anti-osteoporosis drugs in our hospital,the cost of bisphosphonates increased quickly,and the daily cost of zoledronic acid was the highest. Conclusion The application of anti-osteoporosis drugs can promote the rational use and clinical monitoring with great significance.

关 键 词：抗骨质疏松药 药物利用度 限定日剂量 

分 类 号：R96[医药卫生—药理学]