巳时未时电针对脑血栓患者TXA_2、PGF_(1α)的影响与其基础状态的数量关系  

Effects of 9-11 Am and 1-3 Pm Electroacupuncture on TXA_2 and PGF_(1α) and Their Quantitative Relationships with the Basic Status in Cerebral Thrombosis Patients

作　　者：郭珊珊[1] 陈少宗[1] 李艳梅[1] 卜彦青[1] 

机构地区：[1]山东省中医药研究院针灸研究所,济南250014

出　　处：《上海针灸杂志》2010年第8期495-497,共3页Shanghai Journal of Acupuncture and Moxibustion

基　　金：山东省中医药科技发展计划课题(2007-011)

摘　　要：目的探索针刺效应的强弱与机能状态之间的数量关系,寻找针刺效应产生的规律性。方法以30例脑血栓患者为观察对象进行电针,巳时和未时各治疗15例。主穴取患侧足三里、丰隆、三阴交、太溪、曲池、内关、合谷。配穴根据病位不同灵活取用。进针得气后接G6805治疗仪30 min。每天治疗1次。连续治疗5次为1个疗程,治疗3个疗程后进行总结。所有患者在针刺前一天8:00-8:10、针刺3个疗程后次日8:00-8:10抽取静脉血5 mL,离心后分离血清并超低温冷冻保存备检血栓素B2(TXB2)、前列腺素F1α(PGF1α)。结果电针治疗3个疗程后本组患者的TXB2、PGF1α、TXB2/PGF1α都能够获得十分明显的改善,而且电针疗法对TXB2、PGF1α、TXB2/PGF1α的改善程度均与针刺之前TXB2、PGF1α、TXB2/PGF1α的基础水平具有十分密切的直线数量关系,三者的相关系数分别为r=0.752>r0.01(28)、P<0.01,r=0.652>r0.01(28)、P<0.01,r=0.773>r0.01(28)、P<0.01。结论结果表明,在一定范围之内,针刺调节效应的大小机能状态偏离正常水平越明显,也就越显著。Objective To investigate the quantitative relationship between the intensity of acupuncture effect and the functional state and ascertain the regularity of acupuncture effect generation.Methods Thirty cerebral thrombosis patients were enrolled as subjects.Fifteen patients were given electroacupuncture at 9-11 am and the other 15,at 1-3 pm.The main points selected were Zusanli（ST 36）,Fenglong（ST 40）,Sanyinjiao（SP 6）,Taixi（KI 3）,Quchi（LI 11）,Neiguan（PC 6） and Hegu（LI 4） on the affected side.The adjunct points were selected according to different affected parts.A G6805 health device was connected after arrival of qi following needle insertion.Treatment was administered 30 min once daily,5 consecutive times as a course.A summary was made after 3 courses of treatment.In all the patients,5 ml venous blood was drawn at 8：00-8：10 on the day before acupuncture and after 3 courses of acupuncture treatment.Serum was separated by centrifugation and kept by refrigeration at ultralow temperature for the examination of thromboxane B2（TXB2） and prostaglandin F1α（PGF1α）.TXB2,PGF1α and TXB2/PGF1α all improved markedly in the patients after 3 courses of acupuncture treatment.The degrees of improvements in TXB2,PGF1α and TXB2/PGF1α by electroacupuncture therapy had very close linear quantitative relationships with the basic levels of them before acupuncture.The three correlation coefficients were r=0.752r0.01（28）,P0.01;r=0.652r0.01（28）,P0.01;r=0.773r0.01（28）,P0.01,respectively.Conclusion The results indicate that in a certain range,the more obviously the functional state deviates from the normal level,the more marked regulating effect acupuncture produces.

关 键 词：中风 脑血管意外 电针 血栓素B2 前列腺素F1Α 针灸效应 

分 类 号：R246.6[医药卫生—针灸推拿学]