儿童哮喘控制测试及哮喘患儿生命质量量表在支气管哮喘规范化管理中的应用  

Application of Children Asthma Control Test and Pediatric Asthma Quality of Life Questionnaire in Childhood Asthma Standardized Management

作　　者：马春艳[1] 王鑫[1] 张亚京[1] 周芳[1] 宁立华[1] 周蕊[1] 

机构地区：[1]内蒙古医学院第三附属医院儿科,内蒙古包头014010

出　　处：《实用儿科临床杂志》2010年第16期1233-1235,共3页Journal of Applied Clinical Pediatrics

摘　　要：目的探讨儿童哮喘控制测试(C-ACT)及哮喘患儿生命质量量表(PAQLQ)在儿童哮喘规范化管理中的作用。方法选择支气管哮喘患儿77例,随机分为管理组39例,对照组38例。管理组按2008版全球哮喘防治创议指南对哮喘儿童规范治疗,并进行哮喘知识教育,制定个体化治疗方案,定期随访;对照组儿童未进行哮喘知识教育,仅进行发作期治疗。入选患儿在治疗前及治疗3个月分别进行1次C-ACT、PAQLQ填写,同时进行肺功能检测。结果管理组与对照组管理前C-ACT得分无统计学差异(P=0.237);管理后,2组C-ACT得分与管理前比较均显著提高(Pa=0.000);管理组C-ACT得分增加值显著高于对照组(Pa=0.004);管理前后C-ACT得分及增加值与肺功能一秒钟用力呼气量(FEV1)均呈正相关(Pa<0.001),与哮喘控制水平均呈正相关(Pa<0.001)。管理组与对照组管理前PAQLQ各维度得分比较差异无统计学意义;管理后,2组各维度得分与管理前比较均显著提高(Pa=0.000);管理组管理后各维度得分及管理前后得分增加值均显著高于对照组;管理前后PAQLQ量表各维度得分与肺功能FEV1增加值均呈正相关。结论在儿童哮喘规范化管理中,同时应用C-ACT与PAQLQ可以为临床提供简单、有效且能全面评价哮喘疗效的方法 。Objective To explore the application of childhood asthma control test（C-ACT）and pediatric asthma quality of life questionnaire（PAQLQ） in the management of asthma in children.Methods In randomized 77 cases with asthma were divided into management group（39 cases） and control group（38 cases）.The patients in management group were educated standardized management according the global initiative for asthma（GINA） in 2008,the patients in control group were not educated,only had a cure of attack period.All asthmatic patients were enrolled in the C-ACT and PAQLQ trial,and C-ACT and PAQLQ were performed at beginning and 3 months after management,pulmonary function was tested at the same time.Results There was no significant difference of C-ACT scores at the beginning between management group and control group（P=0.237）,but in the both groups,there were significant higher C-ACT scores at posttreatment campared with those at beginning （Pa=0.000）;in management group,C-ACT increased score was significantly higher than that in control group at posttreatment （P=0.004）;C-ACT score and C-ACT increased score were correlated with forced expiratory volume in one second（FEV1%） （Pa〈0.001）.The differences of every dimension PAQLQ scores were not significant at beginning between management group and control group,but there were significan differences at posttreatment campared with those at beginning （Pa=0.000）;in management group,every dimension PAQLQ scores and increased scores were significantly higher than those in control group at posttreatment;every dimension PAQLQ scores were correlated with FEV1%.Conclusion C-ACT and PAQLQ are effective method to assess treat efficacy in standardized management of athmatic patients.

关 键 词：哮喘 儿童哮喘控制测试 哮喘患儿生命质量量表 肺功能 儿童 

分 类 号：R725.6[医药卫生—儿科]