二次正交旋转组合设计法优化赤芍醇提工艺  

Quadratic-Orthogonal-Rotation-Combination Design for Optimization of Ethanol Extraction Craft from Radix Paeoniae Rubra

作　　者：彭晓霞[1] 张振巍[1] 

机构地区：[1]甘肃中医学院,甘肃兰州730000

出　　处：《中药材》2010年第6期991-994,共4页Journal of Chinese Medicinal Materials

摘　　要：目的:二次正交旋转组合设计法优化赤芍醇提工艺。方法:以芍药苷提取率为指标,乙醇浓度、提取时间、乙醇用量为考察因素,采用二次正交旋转组合设计法优选回流提取工艺条件,并进行预测分析。结果:最优提取工艺为:乙醇浓度73%,提取时间100 min,乙醇用量8.3倍。结论:中心组合设计法具有应用简便、预测性好等优点。Objective： To optimize the ethanol extraction process of Radix Paeoniae Rubra（RPR） using quadratic-orthogonal-rotation-combination design.Methods： The influential factors were ethanol volume,ethanol concentration and extracting time.The evaluating indicator was the extraction rate of peoniflorin.The quadratic-orthogonal-rotation-combination design was used to optimize the process and the prediction was carried out.Results： The optimum conditions of extraction were 73% ethanol,100 min for extraction,volume of ethanol was 8.3 times.Conclusion： It shows that the optimum model is simple and highly predictive.

关 键 词：赤芍 二次正交旋转组合设计 提取工艺 

分 类 号：R284.2[医药卫生—中药学]