45例系统性红斑狼疮临床及病理分析  

Clinical and Pathologic Analysis in 45 Patients with Systemic Lupus Erythematosus

作　　者：唐莉[1] 王红梅[1] 

机构地区：[1]天津市长征医院,天津300120

出　　处：《中国中西医结合皮肤性病学杂志》2010年第4期222-224,共3页Chinese Journal of Dermatovenereology of Integrated Traditional and Western Medicine

摘　　要：目的探讨系统性红斑狼疮(SLE)的临床及组织病理学特点。方法回顾分析天津市长征医院2003年1月—2007年2月住院的SLE患者临床表现及组织病理学特点。结果发病高峰为10～40岁,以女性为多;临床表现分析显示,蝶形红斑、光敏、关节痛、脱发最为常见症状,其次为雷诺现象及发热;实验室指标分析显示,ANA、ENA、ds-DNA、免疫球蛋白/补体异常阳性率较高;男性组与女性组比较临床表现及实验室指标均有差异;SLE组织病理学特征变化多样,狼疮带试验在SLE的诊断中十分重要。结论 SLE患者临床表现及组织病理学表现多样。Objective To analyze the clinical and pathologic features of systemic lupus erythematosus（SLE）. Methods 45 cases of SLE patients from Tianjin Changzheng hospital were collected and analyzed retrospectively. Results The high prevalence clinical feature was butterfly facial erythema, photosensitive, arthralgia, alopecia. The second was Raynaud＇s phenomenon and fever. The immunologic features were ANA, ENA, ds-DNA and immunoglobulin/serum complement. There was difference between male group and female group. Lupus band test（LBT） is specific for the diagnosis of SLE. Conclusion The clinical and pathologic features of SLE is multiple.

关 键 词：系统性红斑狼疮 临床表现 实验室指标 组织病理 

分 类 号：R593.241[医药卫生—内科学]