5-氨基水杨酸的简便合成方法  

A CONVENIENT METHOD ON SYNTHESIS OF 5-AMINOSALICYLIC ACID

作　　者：刘加庚[1] 徐瑞均 徐元植[1] 刘瑞庭[2] 

机构地区：[1]浙江大学化学系,杭州310027 [2]舟山市环保监测站,定海310000

出　　处：《精细石油化工》1999年第2期44-46,共3页Speciality Petrochemicals

摘　　要：以水杨酸为起始原料 ,在碱性介质中与苯胺重氮盐进行偶合 ,然后用连二亚硫酸钠还原得到的产物合成标题化合物。该法收率高 ,产物纯 ,而且工艺简便 ,易于工业化规模生产。aminosalicylic acid was prepared from salicylic acid through coupling it with diazotized aniline chloride in basic medium to form azointermediate, and then reducing the intermediate with sodium hydrosulfide to yield the raw product. The raw product was refined efficiently, and the product was obtained in high yield and super quality.

关 键 词：氨基水杨酸 偶合 还原 合成 

分 类 号：TQ246.37[化学工程—有机化工]