勃起功能障碍与血管内皮功能相关性研究及其影响因素  

Correlation and risk factors between vascular endothelial dysfunction and erectile dysfunction

作　　者：朱郇荣[1,2] 孙祥宙[1] 黄燕平[1] 张亚东[1] 刘贵华[1] 姚凤娟[1] 孙宇[2] 邓春华[1] 

机构地区：[1]中山大学附属第一医院泌尿外科,广州510080 [2]广州市第八人民医院泌尿外科

出　　处：《北京大学学报（医学版）》2010年第4期418-420,共3页Journal of Peking University:Health Sciences

摘　　要：目的:探讨血管内皮功能损害与勃起功能障碍(erectile dysfunction,ED)的相关性及其影响因素。方法:选择中山大学附属第一医院泌尿外科就诊的134例ED患者行病史记录,血睾酮、甘油三酯与总胆固醇检测,用彩色多普勒超声检测血管内皮功能,并与对照组(15例健康志愿者)进行比较分析。结果:134例ED患者中97例(72.4%)的血管内皮舒张功能值(flow mediated dilation,FMD)<10%(7.46%±1.66%),与正常对照组相比,差异有统计学意义(P<0.01),血睾酮、甘油三酯与总胆固醇两组差异无统计学意义(P均>0.05),内皮功能影响因素主要有吸烟和运动。结论:大部分青年、中年ED患者与血管内皮舒张功能下降相关,吸烟和缺乏运动可能是ED的主要原因。Objective：To study the correlation between risk factors of vascular endothelial dysfunction and erectile dysfunction（ED）.Methods：The case history records levels of cholesterol,triglyeride and testicle,endothelial functions detected by using Doppler ultrasound and the risk factors of 134 ED patients were analyzed with those of 15 healthy men as the control group.Results：We found that flow mediated dilation（FMD） 〈10% in 97 erectile dysfunction patients among the 134 cases was significantly different from that of the control group with no significant differences in cholesterol,triglyeride and testicle levels.Smoking and lack of exercise might be the high risk factors of vascular endothelial dysfunction.Conclusion：Erectile dysfunction may be linked to the impaired the endothelial function.

关 键 词：勃起功能障碍 内皮 血管 血管舒张 危险因素 

分 类 号：R698.1[医药卫生—泌尿科学]