电位滴定与人工滴定测定消毒灭菌剂中戊二醛含量的比较  

Comparison determination of glutaraldehyde concentration between potentiometric titration and manual titration

作　　者：朱军生[1] 梁建生[1] 刘小丽[1] 徐云斌[1] 邓兵[1] 徐桂兰[1] 

机构地区：[1]武汉市疾病预防控制中心,武汉430015

出　　处：《中国卫生检验杂志》2010年第8期1871-1872,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:电位滴定测定消毒灭菌剂中戊二醛的含量,并与人工滴定的酸碱滴定法比较。方法:以0.25 mol/L硫酸溶液为标准滴定液,分别采用电位滴定和酸碱滴定法测定消毒灭菌剂中戊二醛的含量,并将测定结果计算变异系数、建立直线回归方程。结果:对2.0%～2.2%的戊二醛含量进行测定时,两种方法在相关试剂静置反应时间为60～90 m in时反应平稳、戊二醛含量稳定。电位滴定变异系数(0.08%)明显低于人工滴定(0.60%),其中电位滴定法在戊二醛含量为0.5%～2.0%的范围内,与硫酸滴定液呈完全的线性相关(r=1.000)。结论:采用电位滴定法测定消毒灭菌剂中戊二醛的含量,具有终点容易判断、误差小、精密度高等优点,值得推广应用。Objective：It will use potentiometric titration to determine the glutaraldehyde concentration in disinfection and sterilization agent,and compare with manual titration of the acid-base titration.Methods： With 0.25 mol/L sulfuric acid solution as the standard titration solution,it will respectively use potentiometric titration and acid-base titration to determine glutaraldehyde concentration in disinfection and sterilization agent,and also use the outcome to calculate the coefficient of variation and establish the linear regression equation.Results： When glutaraldehyde concentration is between 2.0% and 2.2%,the reaction of the two methods is stable in 60～90 min.the coefficient of variation of potentiometric titration（0.08%）is significantly lower than manual titration（0.60%）,when glutaraldehyde concentration determined by potentiometric titration is between 2.0% and 2.2% it is highly relevant with sulfuric acid titration solution（r=1）.Conclusion： It has several advantages,such as easy to judge the endpoint,little error,high precision and so on,when using potentiometric titration to determine glutaraldehyde concentration in disinfection and sterilization agent.It is worth to spread.

关 键 词：电位滴定 人工滴定法 戊二醛 含量测定 

分 类 号：O655.22[理学—分析化学]