2007年-2009年金黄色葡萄球菌医院感染现状及耐药性分析  

Study on antibiotic resistance and nosocomial infections status of Staphylococcus aureus in hospital from 2007 to 2009

作　　者：杨丽玮[1] 王玲玲[1] 

机构地区：[1]新疆维吾尔自治区人民医院检验科,乌鲁木齐830001

出　　处：《中国卫生检验杂志》2010年第8期1979-1980,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:了解我院金黄色葡萄球菌(金葡菌)感染现状及耐药情况,为临床诊断疾病与合理使用抗菌药物提供科学依据。方法:回顾性分析我院2007年-2009年来临床各类送检标本中金黄色葡萄球菌的标本分布、耐药性状况及感染趋势。结果:分离出的1102株金黄色葡萄球菌主要来源于痰、伤口、分泌物、体液;药敏结果显示,金黄色葡萄球菌对常用抗生素均有较高耐药,但尚未发现对万古霉素耐药菌株,对糖肽类抗菌药物和新型抗菌药物利奈唑胺敏感率为100.0%;同时检出菌株有逐年增高趋势。结论:金黄色葡萄球菌对常用抗菌药物显示多药耐药,医院应切实进行抗菌药物使用管理,延缓金黄色葡萄球菌临床株耐药性的增长,控制医院感染的暴发流行。Objective：To investigate the antibiotic resistance and nosocomial infections status of Staphylococcus aureus（SAU） and provide scientific evidence for disease diagnose and reasonable use of antibiotics.Methods：Retrospective review was performed to analyzed the specimen′s clinical distribution,antibiotic resistance,and nosocomial infections status of SAU from 2007 to 2009.Results：1102 strains of SAU was mainly isolated from sputum,wounds,secretion,and body fluid.The results of susceptibility test showed that SAU had been resistant to the commonly used antibiotics in higher degree.The drug sensitivity rate of glycopeptide antibiotics and linezolid all were 100 %,but the vancomycin-resistance strains were not observed.Meanwhile,the detected strains increased year by year.Conclusion：SAU shows multidrug resistance to the commonly used antibiotics.In ord to postpone the development of durg-resistance and to prevent the prevalence of nosocomial infections,the monitoring and controlling should be strengthened.

关 键 词：金黄色葡萄球菌 分布 耐药性 医院感染 

分 类 号：R378.11[医药卫生—病原生物学]