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出 处:《生命科学》2010年第8期736-742,共7页Chinese Bulletin of Life Sciences
基 金:国家自然科学基金项目(30871457);教育部长江学者和创新团队发展计划(IRT0635)
摘 要:促分裂原活化蛋白激酶(MAPK)级联途径信号通路在真核生物细胞信号的转换和放大过程中起重要作用。MAPK级联途径由三个成员组成,分别是MAPK、MAPKK及MAPKKK,此三个信号组分按照MAPKKK-MAPKK-MAPK的方式依次磷酸化将外源信号级联放大向下传递。大量研究表明,植物MAPK级联途径参与调控脱落酸(ABA)信号转导。因此,该文就ABA和MAPK的生物学功能、ABA信号转导中的磷酸化与去磷酸化以及MAPK级联途径与ABA信号转导之间的关系等方面的研究进展进行综述,以便进一步认识MAPK和ABA信号转导的分子机制。The mitogen-activated protein kinase(MAPK) cascade plays an important role in signal conversion and amplification of extracellular stimuli in eukaryotic organisms.The MAPK cascade is composed of MAPK,MAPKK and MAPKKK.They transfer signals through phosphorylation of MAPKKK-MAPKK-MAPK in turn.Evidences indicated that MAPK cascades were involved in the regulation of plant ABA signalling.This paper reviews the recent progress in the biological functions of ABA and MAPK,phosphorylation/dephosphoryla-tion in ABA signal transduction and the relation between MAPK cascades and ABA signal transduction in order to provide insights into the molecular mechanism of MAPK and ABA signal transduction.
关 键 词:MAPK级联途径 脱落酸(ABA)信号转导 植物 环境胁迫
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