钯催化以新型亲电试剂为底物的Suzuki偶联反应性能研究  

Study on Suzuki Cross-Coupling Reactions of Novel Electrophilic Substrate with Phenyl Boronic Acid Catalyzed by Palladium

作　　者：南光明[1] 程素玲[1] 刘美英[1] 付建华[1] 李佳[1] 

机构地区：[1]新疆伊犁师范学院化学与生物科学学院,新疆伊宁835000

出　　处：《西南大学学报（自然科学版）》2010年第7期66-70,共5页Journal of Southwest University(Natural Science Edition)

摘　　要：在氩气保护下,室温催化实现了以芳基三氮烯和苯硼酸为底物的Suzuki偶联反应.考察了催化剂、溶剂、两底物物质的量比、催化剂用量等影响反应收率的关键因素,得到了最佳的反应条件,并对底物的普适性进行了研究,结果表明,收率优良.The Suzuki cross-coupling of aryltriazene with phenylboronic acid catalyzed by transition metal catalyst was achieved.The reaction was performed at room temperature under an argon atmosphere.Catalysts,effect of solvent,aryltriazene/phenylboronic acid ratio and the catalyst loading on the cross-coupling reaction were investigated.The scope of this coupling reaction was explored under optimized reaction conditions.Most of the cross-coupling reactions afforded biaryl products in good to excellent yields.The results indicate that this method has good substrate generality.

关 键 词：芳基三氮烯 偶联反应 钯催化剂 

分 类 号：O641[理学—物理化学]