磺酸内铵盐催化烷基苯的氯甲基化反应  

Chloromethylation of Alkylbenes Catalyzed by Sulfonic Ammonium

作　　者：尚洁[1,2] 赵文军[1] 王华[1,2] 王旭[1,2] 宋铁珊[1] 

机构地区：[1]中国科学院新疆理化技术研究所,新疆乌鲁木齐830011 [2]中国科学院研究生院,北京100049

出　　处：《分子催化》2010年第4期333-338,共6页Journal of Molecular Catalysis(China)

基　　金：新疆维吾尔自治区自然科学基金项目(200821158)

摘　　要：烷基磺酸内铵盐相转移催间二甲苯、邻二甲苯分别与多聚甲醛、氯化氢的单氯甲基化反应.通过GC-MS、GC对产物进行定性和定量分析,研究了不同磺酸内铵盐的催化效果,并考察了N-丙磺酸基吡啶盐用量、反应温度、反应时间对间二甲苯和邻二甲苯单氯甲基化反应的影响以及催化剂的重复使用情况.实验结果表明在优化的条件下间二甲苯和邻二甲苯各自的转换率和单氯甲基化的选择性都达到了90%以上,催化剂重复使用4次后,催化剂活性没有明显改变.The Blanc monochloromethylation of m-xylene or o-xylene with paraformaldehyde and hydrogen chloride catalyzed by alkyl-sulfonic ammonium,a phase transfer catalyst has been deveploped.The effect of different ammoniums was investigated.The N-propane sulfone pyridinium was taken an example to study the influence of the amount of catalyst,reaction temperature,reaction time and the repeated use of catalyst.The product was analyzed by GC-MS and GC.The results showed that the conversion of m-xylene or o-xylene and the selectivity of monochloromethylation were over 90% under the optimum conditions.The catalyst could be reused for 4 times without obvious invalidity.

关 键 词：间二甲苯 邻二甲苯 烷基磺酸内铵盐 氯甲基化反应 

分 类 号：O643.32[理学—物理化学]