流动注射化学发光法在分析化学中的研究与应用  

Studies and Application of Flow Injection Chemiluminescence in Analytical Chemistry

作　　者：赵燕芳[1] 张诺[1] 魏琴[1] 韩颜颜[1] 毛珂霞[1] 蔡燕燕[1] 李茹[1] 

机构地区：[1]济南大学化学化工学院,山东省氟化学化工材料重点实验室,山东济南250022

出　　处：《光谱学与光谱分析》2010年第9期2512-2517,共6页Spectroscopy and Spectral Analysis

基　　金：国家自然科学基金项目(20577016);山东省自然科学基金项目(Y2008B44);山东重点学科基金项目(XTD0705);济南市科技发展计划项目(201004015)资助

摘　　要：近年来,流动注射化学发光法作为一种灵敏度高、分析速度快、分析成本低、线性范围宽、仪器设备简单的分析方法,发展迅速,应用广泛。作为一种痕量分析方法,它已经渗透到分析化学的各个领域。首先阐述了流动注射化学发光法的原理和特点,并详细介绍了不同种类化学发光的体系;接着综述了近几年国内外该方法在分析化学领域中药物分析、环境和生命科学监测方面的研究进展,并从测定样品、反应介质、发光体系、线性范围和检出限等诸方面总结和概括了流动注射化学发光法的应用情况;最后针对流动注射化学发光法存在的一些问题提了建议,并对该方法在药物分析、免疫分析、矿物分析、环境监测、临床医药、生命科学等方面广阔的应用前景做了展望。At present,flow-injection chemiluminescence is of high sensitivity,fast analysis,low cost,wide linear response range,and simplified operation for trace analysis,and makes a feature of fast development and wide application.As a trace analysis method,it is infiltrated in diverse areas.The principle and characteristics of flow-injection chemiluminescence were expounded,and the chemiluminescence systems were introduced in detail in the present article.The research developments,which were mainly about drug analysis, environment monitoring and life sciences examination,were summarized,at home and abroad.The application situations of the method were briefed from aspects of determination of sample,the reaction medium,chemiluminescence systems,the linearity range,and the detection limit.Finally,the author proposed suggestions in view of this method to address the ongoing problems,and prospected broad application of flowing injection chemiluminescence in drug analysis,immunoassay, mineralogical analysis,environment monitoring,clinical medicine and life sciences.

关 键 词：流动注射 化学发光 药物分析 环境监测 生命科学 

分 类 号：O657.3[理学—分析化学]