肥胖及相关因素与非胰岛素依赖型糖尿病患病关系的病例对照研究  

A case control study of obesity and correlative factors for NIDDM

作　　者：杨新军[1] 闫洪涛[1] 王建华[2] 王正伦[2] 

机构地区：[1]承德医学院 [2]天津医科大学

出　　处：《中国公共卫生》1999年第3期199-200,共2页Chinese Journal of Public Health

摘　　要：采用１∶１配比病例对照研究方法，对１１０名非胰岛素依赖型糖尿病（ＮＩＤＤＭ）病例的患病危险因素进行研究。条件Ｌｏｇｉｓｔｉｃ回归分析结果表明，开始发胖年龄越早、发胖程度越大患病的危险性越大；既往最大体重指数（ＢＭＩ）大于２８ｋｇ／ｍ２者患病危险性是小于２５ｋｇ／ｍ２者的１１．５２倍。目前的腰围、腰股比（ＷＴＲ）、收缩压（ＳＢＰ）亦与ＮＩＤＤＭ患病有关，而与目前的ＢＭＩ未见有统计学联系。血脂各项显示，总胆固醇（ＴＣ）、甘油三酯（ＴＧ）、载脂蛋白ＡⅠ、Ｂ病例组均高于对照组。多因素调整后，既住最大ＢＭＩ、ＳＢＰ。One hundred and ten pairs of cases and controls from the first Hospital of Tianjing Mediacal University were analyzed in order to investigate the risk factors of non insulin dependent diabetes mellitus(NIDDM).The conditional logistic regression analysis results suggested that the fluctuation of previous weight is an important risk factor for NIDDM.The more the degree of obesity is and the earlier of the age of obesity is the more or increases.Among patients of previous maximal body mass index(BMI)over 28kg/m 2,the odds ratio is 11.52 times that of patients having a previous body mass indes less than 25kg/m 2. Current waist girth,waist thigh ratio(WTR),SBP are also important risk factors for NIDDM.After multiple adjustment previous maximal BMI,SBP,high serun TG remain the independent risk factors for NIDDM.

关 键 词：糖尿病 肥胖 病例对照研究 NIDDM 

分 类 号：R589.2[医药卫生—内分泌] R587.1[医药卫生—内科学]