山东沿海地区痛风和高尿酸血症的流行病学调查  

The Prevalence of Gout and Hyperuricemia in Shandong Province

作　　者：姜宝法[1,2,3,4] 张源潮[1,2,3,4] 徐晓菲[1,2,3,4] 梅唤平 丁峰 王干 丁兆斌[1,2,3,4] 王启松 

机构地区：[1]山东医科大学流行病学教研室 [2]山东医科大学附属医院内科 [3]山东省日照市东港区卫生防疫站 [4]山东省日照市人民医院

出　　处：《中国公共卫生》1999年第3期205-206,共2页Chinese Journal of Public Health

基　　金：山东省科委计划项目资助

摘　　要：调查山东沿海日照、东营、威海及胜利石油管理局共１７０４４人的痛风患病状况和３８４名正常成人血尿酸水平。共发现６例痛风患者，痛风粗患病率为０．０３５２％，标化患病率为０．０３１５％。男女标化患病率之比为１∶０．４１５。男性血尿酸均值为２８９．６±７６．６μｍｏｌ／Ｌ；女性为２３６．５±６３．３μｍｏｌ／Ｌ，二者差异显著。男性高尿酸血症患病率为５．７９％，女性为２．４４％。结果显示。To determine the prevalence of gout and hyperuricemia among the population in eastern coastline area of Shandong Provice,the total of 17044 population in Rizhao,Dong Ying,Weihai,and Shengli oil field were investigated.The serum uric acid was detected by Uricase/trindr method in a random sample that made up of 384 adult normal people.The results showed that crude prevalence of gout was 0 0352% and standardized prevalence was 0 0315%,the ratio of standardizedprevalence in males to females was 1∶0 415.The mean serum uric acid level was 289 6±76μmol/L in males versus 236 5±63 3μmol/L in females.There was a significant difference between males and females.The prevalence of hyperuricemia was 5 79% in males and 2 44% in females.The results suggest that the level of serum uric acid,prevalence of hyperuricemia and gout among population of Shandong Province is significantly lower than the corresponding level in European,American and Southeast Asia.

关 键 词：痛风 高尿酸血症 流行病学 调查 

分 类 号：R589.701[医药卫生—内分泌]