兔胫骨骨折愈合微血管重建的研究  被引量:5

A STUDY ON MICROVASCULAR RECONSTRUCTION IN BONE HEALING OF RABBITS

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作  者:张建国[1] 艾寿坤[1] 黎家华[1] 李兴富[1] 瞿佐发[1] 肖长义[1] 

机构地区:[1]湖北三峡学院医学院解剖学教研室,宜昌443003

出  处:《解剖学杂志》1999年第1期67-70,共4页Chinese Journal of Anatomy

基  金:湖北省教委科学基金资助

摘  要:目的 :为澄清骨折愈合微血管重建意见的分歧。方法 :实验用兔 2 4只 ,4只用于正常胫骨血管观察 ,另 2 0只制成骨折模型。术后分别按 3,8,18,2 8,4 2天处死 ,观察微血管重建。结果 :( 1)微血管数量生长可分为三个时期 :初期 (约 1周 )骨折部位无或有少量新生血管 ;中期 ( 2~ 4周 )血管形成达最高峰 ;后期 ( 5周以后 )血管数量减少并逐渐转为正常形成。 ( 2 )侧支循环的建立是多源的 ,包括从骨膜动脉到骨痂 ;从骺 -干骺动脉到髓腔 ;从皮质纵血管系统到骨痂。结论 :滋养动脉 ,骺 -干骺动脉 。Objective: To clarify the microvascular reconstruction in bone healing. Methods: 24 rabbits were used. 4 rabbits were killed and performed ink perfusion on the tibia to survey the pattern of blood supplies. Others received simulated fracture on the tibia and were kiled in 3,8,18,28, 42 days respectively after the microvascular reconstruction. Results: 1. The amounts of vessels increased at the early stage(1 week ) and rose to the most abundance at the middle stage(2~4) and decreased, still then, translated into normorl pattern of the cortical bone at the late stage(5 week); 2. The collateral circulation of fracture included from periostem to callus; epiphyseal and metaphyseal ateries to marrow; longitudinal vessels of the cortical bone to the callus. Conclusion: It suggested that nutrient, epiphyseal metaphyseal periosteal arteries were important to the reconstruction of the collateral circulation in bone healing.

关 键 词:胫骨骨折 骨折愈合 微血管重建 

分 类 号:R683.42[医药卫生—骨科学]

 

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