颈总动脉内中膜厚度及内径在动脉硬化中的诊断价值  

The Value of Carotid Intima-Media Thickness and Diameter in Diagnosis of Atherosclerosis

作　　者：顾琛琛[1] 李青[1] 郭立志[1] 

机构地区：[1]天津中医药大学第二附属医院,300150

出　　处：《天津医药》2010年第8期660-662,共3页Tianjin Medical Journal

基　　金：国家重点基础研究发展计划(973计划)中医病因病机的理论继承与创新研究项目(项目编号:2006CB504505)

摘　　要：目的:应用超声测量评价颈总动脉内-中膜厚度(IMT)、颈总动脉内径(Dd)与颈动脉粥样硬化(CAS)间的关系。方法:根据纳入标准分为高血压中、高危组40例和高血压低危组40例,应用PHILIPS IU22彩色多普勒超声诊断仪,对2组患者行颈总动脉超声检查,记录每例受检者双侧颈总动脉IMT和Dd。结果:(1)高血压中、高危组IMT和Dd明显高于低危组(P<0.05)。(2)高血压中、高危组IMT或Dd单独异常率、联合异常率与低危组相比差异有统计学意义(P<0.05或P<0.01)。(3)在调整年龄、性别、吸烟、家族史后,血压、血糖、血脂仍对IMT和Dd增加起着较为积极的作用。结论:颈总动脉IMT的增加,Dd的增大可作为反映CAS的客观指标,并且两者同时异常对CAS的评价更具敏感性。Objective：To evaluate the relationship between common carotid artery （CCA） intima-media thickness （IMT）, common carotid artery diameter （Dd） and carotid artery atherosclerosis （CAS） by ultrasonograph. Methods： The carotid arteries were assessed by PHILIPS IU22 color doppler ultrasonography in 40 patients with hypertension of high-risk group and 40 of mild dangerous group. IMT and Dd of common carotid arteries were measured in the two groups. Results： （1）The values of IMT and Dd were significantly higher in hypertensive patients of high-risk group than those of the mild dangerous group （P 0.05）. （2）There were significant differences in isolated abnormal rates of IMT or Dd, and both IMT and Dd in hypertensive patients of high-risk group compared with those of mild dangerous group（P 0.05 or P 0.01）. （3） After adjusting for age, gender, smoking and family history, the levels of blood pressure, blood glucose and blood fat still play an extremely positive role in the increasing of IMT and Dd. Conclusion： The enlargement of common carotid artery IMT and Dd was an objective marker to CAS, but coexistent abnormalities of IMT and Dd were more sensitive to CAS.

关 键 词：动脉粥样硬化 颈总动脉 超声检查 多普勒 彩色 高血压 血糖 脂类 LOGISTIC模型 

分 类 号：R541.4[医药卫生—心血管疾病]