应用ROC曲线评价UF-50在尿路感染中的价值  

To evaluate the application of UF-50 automated urinalysis analyzer in screening urinary tract infection with ROC curve

作　　者：张晋会[1] 马凯[1] 赵瑞峰[1] 刘桂芬[2] 

机构地区：[1]山西省晋城煤业集团总医院,山西晋城048006 [2]山西医科大学公共卫生学院,太原030001

出　　处：《中国卫生检验杂志》2010年第9期2227-2229,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的:探讨UF-50尿沉渣分析仪筛检尿路细菌感染的临床价值。方法:利用2007年完成649人以临床最终诊断为金标准的尿路感染筛查试验结果,绘制受试者工作特征性(ROC)曲线,评价UF-50诊断尿路感染的可靠性。结果:UF-50尿沉渣分析仪中细菌、白细胞、红细和上皮细胞在鉴别尿路细菌和非细菌感染的ROC曲线下面积(AUC)分别为0.91(男)和0.84(女)、0.98(男)和0.93(女)、0.85(男)和0.79(女)和0.91(男)和0.87(女)。结论:应用UF-50尿沉渣分析仪对中段尿细菌数进行定量分析不失为尿路感染诊断一个快速、有效的方法,可利用其阴性预期值高的特点对检验结果阴性的标本进行筛检以减少无效劳动。但应注意假阴性,更不可替代尿定量细菌培养。Objective：To study the clinical significance of screening urinary tract infection by Sysmex UF-50 automated urinalysis analyzer.Methods： A screening study for urinary tract infection in General Hospital of Jincheng Anthracite Mining Group Co.Ltd in 2007,where 649 people had been tested for clinical diagnose criteria as gold standard.Receiver operating characteristics（ROC） curves were drawn to evaluate the reliability of UF-50 automated urinalysis analyzer in ell diagnosing urinary tract infection by counting the bacteria（BACT） and white blood cel（WBC）l and red blood cell（RBC） and epithelial cell（EC） in urine.Results： The areas under ROC curve of BACT and WBC and RBC and EC count for differentiating urinary tract infection were 0.91（men）and 0.84（women）,0.98（men） and 0.93（women）,0.85（men） and 0.79（women）,0.91（men） and 0.87（women）.Conclusion： Using UF-50 to count the BACT and WBC and RBC of the midstream urine is rapid,effective method in diagnosing urinary tract infection.It provides basis for establishing the reference ranges of urinary formed elements of Jincheng and for standard use clinical diagnosis and treatment.We can use the virtue of the negative predictive value to screening the negative specimen so that we can reduce the inefficiency work.But we should caution the false negative specimen and it could not replace the quantitative bacteria culture.

关 键 词：ROC曲线 尿路细菌感染 细菌培养 UF-50尿沉渣分析仪 

分 类 号：R197.39[医药卫生—卫生事业管理]