危重症患者肠功能障碍相关临床因素分析  

The Analysis on Related Clinical Factors in Severe Cases with Intestinal Failure

作　　者：刘晓珺[1] 沈滨[2] 景慧[1] 孙辉[1] 

机构地区：[1]哈尔滨医科大学附属第二医院急诊科,黑龙江哈尔滨150086 [2]哈尔滨医科大学附属第二医院普外科,黑龙江哈尔滨150086

出　　处：《现代生物医学进展》2010年第16期3037-3039,3036,共4页Progress in Modern Biomedicine

摘　　要：目的:研究危重症患者肠功能障碍的相关临床因素,为有效防治肠功能障碍提供理论依据。方法:选取31例合并肠功能障碍的危重症患者为研究对象,以无肠功能障碍的30例危重症患者为对照。研究平均动脉压(MPA)、动脉血氧分压(PaO2),血白细胞计数、钾离子、GPT/GST、白蛋白等指标与肠功能衰竭发生的相关性;分析肠功能衰竭与脏器损伤个数及死亡率的关系。结果:伴有肠功能障碍的危重症患者MPA、PaO2和血清白蛋白水平低于对照组(P<0.05);血白细胞计数和GPT含量明显高于无肠功能障碍组(P<0.05);血钾离子浓度及GST两组无差异(P>0.05);发展至肠功能障碍的患者平均脏器损伤个数多于对照组,并且有着较高的死亡率(P<0.05)。结论:伴有肠功能障碍的危重症患者早期就表现出严重的低血压,低血氧,低白蛋白血症,肝功能的损害,对于这些方面的监测既可以帮助我们早期发现肠功能障碍的存在,也有助于指导早期干预。Objective： To investigate related clinical factors in severe cases with intestinal failure, and to provide the theory which preventation and cure to intestinal disfunction depend on. Method： We chose 31 severe cases with intestinal failure as study object and 30 severe cases without intestinal failure as control object. To investigate the relationship between average arterial pressure （MPA）, arterial partial pressure of oxygen（ PaO2 ）, lencocyte count（ WBC ）, kalium ion concentration, GPT/GST, albumn and intestinal failure; and to analyze the relationship between intestinal failure and mortality and the number of injured organs. Results： The levels of MPA, PaO2 and albumn in study group are lower than those in control group（P〈0.05 ） ;The lencocyte count and GPT in study group are higher than those in control group significantly （P〈0.05）;Kalium ion concentration and GST have no difference in both groups （P〉0.05）. The averaged number of injured organs resulted from intestinal failure patients is higher than those in control group, and there is a higher mortality in the former group （P〈0.05）. Conclusion： In early stage there are some severe symptoms such as lower blood pressure, PaO2 and albuminaemia and injure of liver function in those severe cases with intestinal failure. We can not only early discovery the exist of intestinal disfunction by monitoring the upper targets, but also take some messures to do early intervention.

关 键 词：肠功能障碍 临床因素 危重症 

分 类 号：R459.7[医药卫生—急诊医学]