原发性高血压合并糖尿病与脉搏波传导速度关系的探讨  

Relationship between Brachial-ankle Pulse Wave Velocity and Patients with Diabetes and Essential Hypertension

作　　者：彭春花[1,2] 尹淇[1,2] 潘云[1,2] 马敏[1,2] 杨栋[1,2] 盖起明[1,2] 

机构地区：[1]昆明医学院附属延安医院 [2]云南心血管病医院心内科,云南昆明650051

出　　处：《昆明医学院学报》2010年第8期104-106,共3页Journal of Kunming Medical College

摘　　要：目的观察原发性高血压(EH)、原发性高血压合并糖尿病(EH+DM)患者和健康受试者的臂踝脉搏波传导速度(baPWV)差异.方法测定昆明医学院附属延安医院36例EH、35例EH+DM患者及35例健康人的血压、脉压、血糖、血脂、体重指数、血清肌酐及baPWV,并进行比较分析.结果 EH十DM组:空腹血糖显著高于另外两组(P<0.01),体重指数、血清肌酐、收缩压、舒张压、脉压、LDL-C水平显著高于对照组(P<0.01),但与EH组比较无统计学意义(P>0.05).EH组:除血压、脉压、LDL-C水平较对照组显著升高(P<0.01)外,体重指数、空腹血糖、血清肌酐均无统计学意义(P>0.05).baPWV在EH组和EH+DM组均显著高于对照组(P<0.01),EH+DM组又显著高于EH组(P<0.05).结论高血压合并糖尿病者的baPWV显著高于EH者,后者又显著高于健康对照组.baPWV升高与血压、脉压、血糖、低密度脂蛋白升高有关。Objective To observe the difference of brachial-ankle pulse wave velocity（baPWV） among patients with essential hypertension（EH group）,patients with diabetes and essential hypertension（EH＋DM group）,and healthy volunteers.Methods The blood pressure,pulse pressure,blood glucose,blood fat,BMI,creatinine and baPWV were detected and compared among 36 patients with essential hypertension,35 patients with diabetes and essential hypertension and 35 healthy volunteers in our department.Results The fasting blood glucose levels of patients in the EH＋DM group were higher than the other two groups（P〈0.01）.The BMI,creatinine,systolic pressure,diastolic pressure,pulse pressure and low density lipoprotein-cholestero levels of patients in the EH＋DM group were obviously higher than healthy volunteer group（P〈0.01）.The systolic pressure、diastolic pressure,pulse pressure and low density lipoprotein-cholesterol levels of patients in EH group were higher than healthy volunteer group（P〈0.01）.There was no difference in BMI,fasting blood glucose,creatinine between EH group and healthy volunteer group.The baPWV of patients in EH＋DM group and EH group was higher than healthy volunteer group（P〈0.01）.The baPWV of patients in EH＋DMgroup was higher than EH group（P〈0.05）.Conclusions The baPWV in the patients with EH＋DMis higher than EH group and healthy volunteer group.There is a relationship between the rising of baPWV and rising of systolic pressure,diastolic pressure,pulse pressure and lowdensity lipoprotein-cholesterol.

关 键 词：原发性高血压 糖尿病 脉搏波传导速度 

分 类 号：R233[医药卫生—中医学]