银屑病患者病情与扁桃体表面需氧菌群季节性变化的关系  

Relationship Between Seasonal Changes of the Severity of Psoriasis and Aerobic Floras on Tonsil Surface in Psoriatic Patient

作　　者：张书岭[1] 蔡润芳[2] 王瑛[1] 罗予[3] 朱钵[1] 

机构地区：[1]河南省人民医院皮肤科,郑州市450003 [2]河南省人民医院检验科,郑州市450003 [3]河南省医学科学研究所

出　　处：《中华皮肤科杂志》1999年第2期85-86,共2页Chinese Journal of Dermatology

摘　　要：目的通过探讨寻常型银屑病病情与扁桃体表面需氧菌群的季节性变化 ,以揭示微生态失调与银屑病的关系。方法用常规方法对患者的扁桃体表面分泌物进行菌种的定性和定量分析。结果冬季时 ,患者组扁桃体表面部分菌种(肺炎链球菌、B群链球菌和A群链球菌)出现的阳性频次及菌落形成单位明显高于健康人组(P<0.05);而夏季时这种差异变小(P>0.05)。结论患者扁桃体表面微生态失调是银屑病病情变化的原因之一。Objective To study the relationship between seasonal changes of the severity of psoriasis and aerobic floras on the tonsil surface in patients with psoriasis vulgaris.Methods The qualitative and quantitative analyses of aerobic floras of tonsil surface were conducted in psoriatic patients and health controls.Results The frequency of positive culture of some bacterial floras (Streptococcus pneumoniae, S. pyogenes and S. agalactiae) and their CFU/g were significantly higher in the patients than those in normal controls in the winter (P< 0.05);but no significant differences were observed in the summer (P >0.05).Conclusion The above results suggest that microecological imbalance on the tonsil surface of the patients might be one of the causative factors in seasonal changes of the severity of psoriasis.

关 键 词：银屑病 需氧细菌 季节性变化 流行病学 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]