电针刺激对大鼠大脑感觉运动皮层(SmI)的影响  

Effects of Electro-acupuncture on Primary Sensorimotor Cortex (SmI) of Rats

作　　者：王健夫 王晓慧[2] 李成祥 WatersRS McCandlishCA 

机构地区：[1]黑龙江鸡西煤矿高级卫生专科学校中医科,鸡西158100 [2]中国医科大学,沈阳110001 [3]美国田纳西州州立大学医学院解剖系

出　　处：《针刺研究》1999年第1期29-34,共6页Acupuncture Research

摘　　要：本文通过６例大鼠对其一侧前爪第三趾尖进行短期（２小时）电针刺激，研究了大鼠大脑主要感觉运动皮层外周皮肤表面代表区所受的影响。刺激点相当于人类第三指尖上的十宣穴。通过ＳｍＩ皮层电生理触觉功能代表区图，分别测量了第二、三、四趾尖在电针刺激前后代表区的面积。所得资料均作了统计学处理。结果表明第二趾尖代表区于电针刺激前后面积的变化无统计学上的明显差异（Ｐ＞０．０５）；但是，在第三趾尖代表区，电针刺激前图的面积明显大于电针刺激后图的面积，两者之间有统计学上的显著差异（ Ｐ ＜ ０． ０２）；而第四趾尖代表区图面积于电针刺激前后的变化与在第二趾尖代表区图面积的变化相仿，其间亦无统计学明显差异（Ｐ＞０．０５）。结果说明短期电针刺激影响了大脑主要感觉运动皮层外周代表区的组合，并能直接扩大受试点在ＳｍＩ皮层代表区的面积。 本文还从大脑皮层可塑性的角度对其变化机理进行了探讨。其原因之一可能是比原代表区增力。部分的皮层范围内神经元的亚阈值输入改变或提升到能放电的超阈值水平。The effects of electrical stimulation of the tip of rat's forepaw's digit 3 (equivalent to the Shixuan acupoint) on skin representations in primary sensorimotor cortex were studied. The conical representations of digit 2, 3,4 tips were measured before and after stimulation. The results showed that stimulation of digit 3 caused no significant change in representations of tips of digit 2 and 4, but the representation of tip of digit 3 expanded significantly (P < 0. 02). This suggests that electrical stimulation of body Skin has effect of the organization of primary sensorimotor cortex (SmI) and expands the rep- resentation of the stimulated skin area. The mechanism of conical pasticity was discussed. One of the suggested reasons for representation expansion is that the subthreshold responses of neurons in the expanded area may be altered and/or elevated to supra-threshold firing level.

关 键 词：电针 皮层代表区 SMI 脑电 

分 类 号：R245.97[医药卫生—针灸推拿学]