对二乙氨基苯甲醛合成新工艺  

A Novel Synthesis Process of p-Diethylaminobenzaldehyde

作　　者：卞真俊[1] 邢颖[1] 王雪梅[1] 张彦中[1] 祁巍[1] 

机构地区：[1]沈阳化工研究院有限公司,沈阳110021

出　　处：《染料与染色》2010年第4期42-42,34,共2页Dyestuffs and Coloration

摘　　要：在苯溶剂中以双(三氯甲基)碳酸酯(简称BTC)代替三氯氧磷与N,N-二乙基苯胺进行甲酰化反应,合成了对二乙氨基苯甲醛,一次收率达90%以上,产品纯度超过98%。考察各类反应影响因素,确立较适宜的工艺条件为N,N-二乙基苯胺∶DMF∶BTC=1∶1.1∶0.45(摩尔比),反应温度80℃左右,反应时间3小时。POCl3 was replaced by BTC,then p-diethylaminobenzaldehyde was synthesized from BTC and N,N-diethylbenzeneamine by formylation reaction in benzene solvent.The yield was above 90% and the purity was more than 98%.Different influence factors were studied and a suitable process was determined.It was（mole rate）N,N-diethylbenzeneamine∶DMF∶BTC=1∶1.1∶0.45,reaction temperature about 80℃,reaction time 3 hours.

关 键 词：对二乙氨基苯甲醛 双(三氯甲基)碳酸酯(BTC) 甲酰化 

分 类 号：TQ244.1[化学工程—有机化工]