CT灌注成像在肝癌诊断中的应用  

Application of CT perfusion imaging in diagnosing liver cancer

作　　者：吴嘉兴[1] 梅铭惠[1] 

机构地区：[1]桂林医学院附属医院肝胆外科,广西541001

出　　处：《中华肝胆外科杂志》2010年第8期634-637,共4页Chinese Journal of Hepatobiliary Surgery

摘　　要：CT灌注成像（CT perfusion imaging，CTPI）定量测定肝脏局部血流可获取相应肝区的灌注指标，如肝血流量、肝血容量、肝动脉灌注指数等。由于不同组织（正常肝、肝硬化、肝细胞癌、转移性肝癌等）的灌注指标存在差异，通过对相关指标进行分析，可鉴别肝脏占位的性质，尤其可诊断微小肝癌。本文介绍了CTPI的原理，肝细胞癌和转移性肝癌CTPI的鉴别要点，CTPI与微血管密度的关系，TACE前后肝癌CTPI的变化，以及CTPI与超声造影诊断敏感性的比较。Hepatic perfusion data such as hepatic blood flow, hepatic blood volume, hepatic arterial perfusion index etc, can be obtained by CT perfusion imaging （CTPI） with quantitative measurements of local blood flow to the liver. As the data mentioned above are varied in different tis sues, e. g normal liver parenchyma, cirrhotic liver, hepatocellular carcinoma（HCC） and secondary liver cancer（SLC）, the differential diagnosis of liver lesions, especially the early subclinical liver cancer, can be made by analyzing the related data. The principle of CTPI, the main points for differential diagnosis between HCC and SI.C, the relationship between CTPI and micro-vessel density（MVD）, the changes of CTPI pre and post-TACE, as well as diagnostic sensitivity of CTPI and contrast enhanced ultrasound（CEUS） in patients with liver cancer were introduced in this article.

关 键 词：CT灌注 肝癌 诊断 鉴别诊断 

分 类 号：R686[医药卫生—骨科学]