Hydrogen bonded foldamer-bridged biscoumarins:A UV-Vis absorption and fluorescent study of the solvent effect  

作　　者：LU ZhengQuan ZHU YuanYuan LIN JianBin JIANG XiKui LI ZhanTing 

机构地区：[1]Henan Institute of Chemistry, Zhengzhou 450002, China [2]State Key Laboratory of Bio-Organic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

出　　处：《Chinese Science Bulletin》2010年第25期2870-2878,共9页

基　　金：supported by the National Natural Science Foundation of China (20732007,20621062,20672137,20872167);the National Basic Research Program of China (2007CB808001);the Science and Technology Commission of Shanghai Municipality (09XD14-05300)

摘　　要：Three arylamide-bridged biscoumarin derivatives 1-3 have been designed and prepared. Compounds 1 and 2 are induced by the intramolecular N?H…O and N·H…F hydrogen bonding to possess a helical conformation,and 3 is induced to have an extended conformation. A comparison of their absorption and fluorescent spectra in a variety of solvents of a wide range of polarity with those of control compound 4 reveals that,for foldamers 1 and 2,the intramolecular hydrogen bonding and the helical conformations exist in most solvents,but do not exist or are very weak in DMF and DMSO.Three arylamide-bridged biscoumarin derivatives 1-3 have been designed and prepared. Compounds 1 and 2 are induced by the intramolecular N-H…O and N-H…F hydrogen bonding to possess a helical conformation, and 3 is induced to have an extended conformation. A comparison of their absorption and fluorescent spectra in a variety of solvents of a wide range of polarity with those of control compound 4 reveals that, for foldamers 1 and 2, the intramolecular hydrogen bonding and the helical conforma- tions exist in most solvents, but do not exist or are very weak in DMF and DMSO.

关 键 词：紫外可见吸收光谱 分子内氢键 溶剂效应 荧光光谱 极性化合物 螺旋构象 DMSO 衍生物 

分 类 号：O657.32[理学—分析化学] O623.413[理学—化学]