终末期肾病透析期间血糖波动情况及影响因素  

Blood Glucose Fluctuation in Dialysis Patients with End-stage Renal Disease and its Contributing Factors

作　　者：袁璐[1] 马建华[1] 

机构地区：[1]南京医科大学附属南京第一医院内分泌科,南京210006

出　　处：《医学综述》2010年第17期2647-2649,共3页Medical Recapitulate

摘　　要：随着肾功能的进行性恶化,终末期肾病终末期肾脑患者必须依靠透析治疗维持生命,肾功能减退会使糖和胰岛素代谢以及药物的药代动力学发生显著变化,终末期肾脑的血糖控制变得更为棘手。透析过程中容易出现低血糖,糖尿病及高龄患者在透析过程中更易发生低血糖,同时低血糖的发生还与糖尿病治疗方式以及透析液含糖高低有关。在透析过程中应密切监测血糖,根据血糖波动情况调整降糖方案。With the progressive deterioration of renal function,end-stage renal disease（ESRD）patients need to rely on dialysis to sustain life.Renal dysfunction significantly alters the metabolism of glucose and insulin,in addition to the pharmacokinetics of drugs.Glycemic control has become more difficult in ESRD.The process of dialysis is easy to induce hypoglycemia,to which diabetic and elderly patients are more prone.The incidence of hypoglycemia is also associated with diabetes treatment,and the glucose level in dialystic fluid as well.In the process of dialysis,blood glucose should be monitored closely,adjusted to individual circumstances.

关 键 词：终末期肾病 透析 血糖 

分 类 号：R587.2[医药卫生—内分泌] R692.5[医药卫生—内科学]