100例心脏手术Ⅰ类切口围手术期抗生素应用分析  

Analysis of application of antibiotics to type Ⅰ incision of cardiac operations during perioperative period in 100 patients

作　　者：赵培西[1] 刘渝[1] 王婧雯[1] 吴寅[1] 常瑛[1] 朱艳荣[1] 王志睿[1] 文爱东[1] 

机构地区：[1]第四军医大学西京医院药剂科,西安710033

出　　处：《药学服务与研究》2010年第4期293-295,共3页Pharmaceutical Care and Research

摘　　要：目的:调查第四军医大学西京医院心脏手术Ⅰ类切口围手术期抗生素应用现状,探讨提高抗菌药物合理应用的方法。方法:对本院2008年1月-12月100例心脏手术Ⅰ类切口围手术期抗生素使用情况进行回顾分析。结果:所有病例围手术期均使用了抗生素,初次给药时机选择不合理的79例;术后使用抗生素疗程不合理的79例;抗生素选择不合理的4例。发生院内感染8例,细菌培养送检2例。抗菌药物联用情况较好。结论:本院心脏手术围手术期抗生素使用仍存在术前用药时机选择不当、预防用药时间过长和细菌培养送检率低等问题,应继续加强对围手术期抗生素使用的管理,规范其使用。Objective：To explore the application of antibiotics to cardiac surgical procedures during perioperative period in Xijing Hospital affiliated to the Fourth Military Medical University,and to elevate the levels of rational utilization of antibiotics.Methods：Utilization of antibiotics in 100 cases of type Ⅰ incision of cardiac operations from January to December in 2008 was retrospectively analyzed.Results：All patients were administered with antibiotics during perioperative period.The starting time of administration of antibiotics was not correct in 79 cases.The choice of antibiotics was not suitable in 4 patients.Treatment courses of antibiotics after the operation were irrational in 79 cases.Eight patients got nosocomial infection,and 2 cases had bacteria identified（25%）.Conclusion：Irrational use of perioperative antibiotics,such as unsuitable starting time of giving antibiotics,prolonged preventive use of drug and low percentage of bacterial identification,exists in this hospital.It is necessary to strengthen the management and standardize administration of prophylactic use of antibiotics.

关 键 词：抗生素 药物利用评审 心脏外科手术 围手术期 

分 类 号：R978.1[医药卫生—药品] R969.3[医药卫生—药学]