保留子宫血管的子宫切除术对卵巢功能影响的研究  

Effects of Artery-sparing Subtotal Hysterectomy on Ovarian Function

作　　者：徐小凤[1] 周焕娣[1] 李苗[1] 

机构地区：[1]广东医学院附属石龙博爱医院妇产科,广东东莞523320

出　　处：《南昌大学学报（医学版）》2010年第6期18-21,共4页Journal of Nanchang University：Medical Sciences

摘　　要：目的探讨保留子宫血管次全子宫切除术对卵巢内分泌功能及血脂水平的影响。方法将子宫良性病变需行子宫次全切除术75例患者随机分为保留子宫血管次全子宫切除术组(研究组,n=38)和传统次全子宫切除术组(对照组,n=37),比较2组手术时间、术中出血、术后并发症发生率,同时分别于术前,术后3、6个月,术后1、2年抽血查血清性激素水平和检测血脂水平,并进行围绝经期症状临床随访。结果 2组手术时间、术中出血量、术后并发症发生率相比无显著性差异(P>0.05)。研究组手术前后血清性激素及血脂水平无显著差异(P>0.05),围绝经期症状几乎不出现;对照组术后FSH明显增高(P<0.05),E2降低(P<0.05),TC、TG、LDL明显升高(P<0.05),围绝经期症状出现较多。结论保留子宫血管次全子宫切除术对卵巢内分泌功能的影响小于传统次全子宫切除术,该术式不增加手术难度和并发症的发生率。Objective To investigate the effects of artery-sparing subtotal hysterectomy on ovarian function and serum lipid level.Methods Seventy-five patients with ovary benign lesion were randomlly divided into two groups,which were respectively treated with artery-sparing subtotal hysterectomy（study groups,n=38）and traditional subtotal hysterectomy（control groups,n=37）.Average operating time,operating blood loss and postoperative complications were compared between the two groups.Clinical follow-up analysis was performed to evaluate the symptoms of peri-menopausal period and compare the changes of serum hormones and lipid level of postoperative 3 months,6 months,1 year and 2 year,respectively.Results No differences of average operating time,operating blood loss and postoperative complications were observed between groups（P〉0.05）.Study groups showed no significant changes of blood hormones and lipid levels（P〉0.05） after operation,and fewer symptoms of peri-menopausal period.However,control groups showed higher FSH levels（P〈0.05） and lower E2 levels（P〈0.05） with higher TC,TG and LDL（P〈0.05） after operation,and more symptoms of peri-menopausal period.ConclusionsArtery-sparing subtotal hysterectomy showed high value on ovarian function than traditional subtotal hysterectomy,with no increases in operational difficulty and incidence rate of complication.

关 键 词：次全子宫切除术 血清性激素 血脂 围绝经期症状 

分 类 号：R713.42[医药卫生—妇产科学]