高尿酸血症与血压、血脂、血糖关系的研究  

The association of hyperurieemia with blood pressure and blood levels of lipids and sugar

作　　者：吕天越[1] 曾永红[1] 周新华[1] 李宇雄[1] 

机构地区：[1]广东省中医院珠海医院,519015

出　　处：《国际医药卫生导报》2010年第17期2081-2083,共3页International Medicine and Health Guidance News

基　　金：基金项目：广东省中医药局科研课题（2008036）

摘　　要：目的研究健康体检人群高尿酸血症与血压、血脂、血糖的关系。方法采用病例对照方法，以2008年珠海市公务员健康体检中发现高尿酸血症男性患者1129人，女性患者165人为高尿酸组，以性别相同、年龄、职业等因素相近的为对照组，探讨其对血压、血脂、血糖的影响。结果高尿酸血症组收缩压为（132．4±13．1）mmHg、舒张压为（82．1±7．5）mmHg、TG为（2．21±1．43）mmol／L、HDL—C为（1．22±0．31）mmol／L、FPG为（5．92±0．72）mmool／L；对照组收缩压为（128．3±12．8）mmHg、舒张压为（79．5±7．2）mmHg、TG为（1．78±1．38）mmol／L、HDL-C为（1．31±0．33）mmol/L、FPG为（5．80±0．68）mmol／L；两组比较，差异具有极显著性（P〈0.01）。高尿酸组的高血压、血脂异常和空腹血糖升高患病率分别为：28．12％、50．36％、25．04％；对照组的高血压、血脂异常和空腹血糖升高患病率分别为：19．23％、32．86％、16．07％；两组比较，差异具有极显著性（P〈0.01）。结论高尿酸血症与血压、血脂、血糖密切相关，应加强高尿酸血症的健康教育，及早预防。Objective To explore the association of hyperuricemia with blood pressure and blood levels of lipids and sugar in the individuals on regular physical examination. Methods The hyperuricemia group included 1129 male and 165 female individual with hyperuricemia cornfirmed in a regular physical examination for civil servants in 2008. The control group had the matched sex, age, and profession. The effects of hyperuricemia on blood pressure, lipids, and sugar were determined. Results The average levels of systolic and diastolic pressures, TG, HDL-C, and fasting blood sugar were markedly higher in the hyperuricemia group than in the control group ; the rates of hypertension, abnormal lipid levels, and impaired fasting sugar were higher in the hyperuricemia group. Conclusions Hyperuricemia is closely associated with blood pressure and levels of blood lipids and sugar. Health education on hyperuricemia should be strengthened to prevent the occurrence of the disorder earlier.

关 键 词：高尿酸血症 血压 血脂 血糖 

分 类 号：R589[医药卫生—内分泌]