血必净注射液治疗烧伤并发脓毒症患者的疗效观察  

Observation on the anti-inflammatory effect of xuebijing injection on the patients with burns concomitant with sepsis

作　　者：罗戈南 闫立群[2] 

机构地区：[1]青岛公安消防医院,山东266042 [2]青岛海军潜艇学院,山东266071

出　　处：《中国临床新医学》2010年第8期744-746,共3页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

摘　　要：目的观察血必净注射液对烧伤脓毒症患者的抗炎作用。方法将120例烧伤脓毒症患者随机分为治疗组与对照组,均给予常规治疗,治疗组在此基础上给予血必净注射液100ml静脉滴注,2次/d,连用7d,观察两组治疗前后外周血降钙素原(PCT)、C-反应蛋白(CRP)和WBC水平变化及并发症的发生情况。结果治疗组治疗后外周血PCT、CRP和WBC水平明显下降,而对照组则变化不大,治疗组并发症发生率明显低于对照组。结论血必净注射液对炎性因子具有拮抗作用,可改善烧伤脓毒症患者的预后。Objective To evaluate the effecacy of xuebijing injection on patients with burns concomitant with sepsis. Methods One hundred and twenty patients with burns concomitant with sepsis were randomly divided into therapy group and control group, and both were treated with conventional therapy. The therapy group was given xuebijing injection 100 ml intravenous drip twice daily for 7 days in addition. Before and after therapy,the changes of PCT, CRP and WBC in all patients were observed. Results The levels of PCT, CRP and WBC in the therapy group were improved significantly after therapy, but the levels of PCT, CRP and WBC in the control group were non significantly changed. The incidence of complication of therapy group was lower significantly than that of the control group. Conclusion Xuebijing injection possesses antagonistic effect on inflammatory factor in sepsis, and can improve the prognosis of patients with bums concomitant with sepsis.

关 键 词：烧伤 脓毒症 血必净注射液 抗炎作用 

分 类 号：R644[医药卫生—外科学]